CD40, Human, Recombinant, 0.1 mg CD40, Human, Recombinant,  0.1 mg 货号:BM-5093-0.1MG Advanced Biomatrix

2025-08-09

CD40, Human, Recombinant, 0.1 mg

英文名:CD40, Human, Recombinant, 0.1 mg

货号:BM-5093-0.1MG

规格:0.1 mg

品牌: Advanced Biomatrix

报价:¥2050.00

商品描述

Human CD40 (TNRRSF5: tumor necrosis factor receptor superfamily member 5, isoform 2) is a 203 amino acid cell surface protein. This protein belongs to a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Full-length extracellular domain of human CD40 gene (Isoform-II, 21-193 aa) was constructed with 31 N-terminal T7/His tag and expressed in E. coli as inclusion bodies. The final product was refolded using our unique “temperature shift inclusion body refolding” technology and chromatographically purified.

Parameter, Testing, and Method

CD40, Human, Recombinant

Catalog # 5093

Quantity

0.1 mg (100 µg/vial)

Volume

0.2 mL

Concentration

0.5 mg/mL

Purity

>90%

as measured by SDS PAGE

Formulation

Formulated in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, L-Arginine, DTT and Glycerol.

Form

Solution

Production Type

Recombinant – E. coli

Storage Temperature

Keep at -20°C for long term storage. Product is stable at 4 °C for at least 30 days

Shelf Life

12 months after receipt

Sterilization Method

Filtration

Cell Attachment Activity

Passes

Sterility

No growth

Accession Number

NP_690593

Recombinant Protein Sequence

MASMTGGQQMGRGHHHHHHGNLYFQGGEFELEPPTACREK

QYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDT

WNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGW

HCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVG

FFSNVSSAFEKCHPWTRSPGSAESPGGDPHHLRDPVCHPL

GAGL

References Downloads

视频

© 金山科研平台是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://16ao.com/thread-231055.htm
© CD40, Human, Recombinant, 0.1 mg CD40, Human, Recombinant,  0.1 mg 货号:BM-5093-0.1MG Advanced Biomatrix,产品报价联系微信jinshanbio
产品询价需求提交
产品询价请加微信:jinshanbio
返回