CD86, Human, Recombinant, 0.1 mg
英文名:CD86, Human, Recombinant, 0.1 mg
货号:BM-5096-0.1MG
规格:0.1 mg
品牌: Advanced Biomatrix
报价:¥2050.00
商品描述
Human CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. Recombinant CD86 may service as coating matrix protein for studying of T cell functionsin vitro.
Full-length human CD86 extracellular domain cDNA (24 – 247 aa, Isoform-2) was constructed with 31 N-terminal T7/His tag and expressed in E. coli as inclusion bodies. The final product was refolded using our unique “temperature shift inclusion body refolding” technology and chromatographically purified as soluble protein
Parameter, Testing, and Method
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CD86, Human, Recombinant Catalog # 5096
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Quantity
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0.1 mg (100 µg/vial)
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Volume
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0.2 mL
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Concentration
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0.5 mg/mL
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Purity
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>90% as measured by SDS PAGE
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Formulation
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Formulated in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, L-Arginine, DTT and Glycerol.
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Form
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Solution
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Production Type
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Recombinant – E. coli
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Storage Temperature
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Keep at -20°C for long term storage. Product is stable at 4 °C for at least 30 days
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Shelf Life
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12 months after receipt
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Sterilization Method
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Filtration
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Cell Attachment Activity
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Passes
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Sterility
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No growth
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Accession Number
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NP_008820
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Recombinant Protein Sequence
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MASMTGGQQMGRGHHHHHHGNLYFQGGEFELPLKIQAY FNETADLPCQFANSQNQSLSELVVFWQDQENLVLNEVYL GKEKFDSVHSKYMGRTSFDSDSWTLRLHNLQIKDKGLY QCIIHHKKPTGMIRIHQMNSELSVLANFSQPEIVPISNITE NVYINLTCSSIHGYPEPKKMSVLLRTKNSTIEYDGIMQKS QDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTRLLS SPFSIELEDPQPPPDHIP |
References Downloads
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CD86, Human, Recombinant, 0.1 mg CD86, Human, Recombinant, 0.1 mg 货号:BM-5096-0.1MG Advanced Biomatrix,产品报价联系微信jinshanbio
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