m7GpppG Cap

N-7001mCAP (m7G(5')ppp(5')G Cap Analog)

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Reference（s） Probst J, et al. Characterization of the ribonuclease activity on the skin surface. （2006） Genetic Vaccines and Therapy. 4（4）. Kariko, K., Buckstein, M., Ni, H. & Weissman, D. Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modifiation and the Evolutionary Origin of RNA （2005）. Immunity, 23（2）, 165-175. Ahola T, Kaariainen L. Reaction in alphavirus mRNA capping: formation of a covalent complex of nonstructural protein nsP1 with 7-methyl-GMP. （1995） Proc Natl Acad Sci U S A, 92（2）: 507-11. Konarska MM, Padgett RA, Sharp PA. Recognition of cap structure in splicing in vitro of mRNA precursors. （1984） Cell. 38（3）:731-6. Miura K. The cap structure in eukaryotic messenger RNA as a mark of a strand carrying protein information. （1981） Adv Biophys. 14:205-38. Banerjee AK. 5'-terminal cap structure in eucaryotic messenger ribonucleic acids. （1980） Microbiol Rev. 44（2）:175-205. Rosenberg M, Paterson BM. Efficient cap-dependent translation of polycistronic prokaryotic mRNAs is restricted to the first gene in the operon. （1979） Nature. 21;279（5715）:696-701. Filipowicz W. Functions of the 5,-terminal m7G cap in eukaryotic mRNA. （1978） FEBS Lett. 96（1）:1-11. Zan-Kowalczewska M, Bretner M, Sierakowska H, Szczesna E, Filipowicz W, Shatkin AJ. Removal of 5'-terminal m7G from eukaryotic mRNAs by potato nucleotide pyrophosphatase and its effect on translation. （1977） Nucleic Acids Res. 4（9）:3065-81.

N-7001-1 mCAP 1umole 1317.5 N-7001-10 mCAP 10umoles 10625 N-7001-5 mCAP 5umoles 6205