Jo-1 antigen

Identity:Histidyl tRNA synthetase, HisRS, histidine translase.Source Material:Bovine thymus (New Zealand origin).Clinical Indications:Autoantibodies present in polymyositis, dermatomyositis.Ordering I

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AROTEC_Jo-1_MSDS.pdfVersion/Date: B/04.05.26MATERIAL SAFETY DATA SHEETProduct: Jo-1 antigen, from bovine thymusSynonym: Histidyl-tRNA Synthetase / Histidine-tRNA Ligase / HISRSE.C. No.: 6.1.1.21CAS Registry No.: not availableCatalog No.: ATJ01-02, ATJ01-05, ATJ01-10*****************************************************************************************Page 1 of 3AroTec Diagnostics Limited, 10 Hutt Road, Petone, P.O. Box 38586 Wellington Mail Centre, Wellington 6332, New Zealand +64-4-5690361 ¬ +64-4-5690366 : info@arodia.comComposition InformationChemical Formula/Composition: N/APhysical Description: Clear, colourless liquid/frozen liquidStability/Reactivity: Stable. Hazardous decomposition or polymerization will not occur.*****************************************************************************************Hazard Identification（s）Hazards identified with this product are those associated with the following component（s）:Glycerol, DNase, RNase and Protease freeCAS Registry No.: 56-81-5Concentration: 20% v/vPotential Health Effects:Eye: May cause mild eye irritation.Skin: May cause mild skin irritation. Low hazard for usual laboratory handling.Ingestion: May cause gastrointestinal irritation with nausea and diarrhoea. May causeheadache. Expected to be a low ingestion hazard.Inhalation: Low hazard for usual laboratory handling. Inhalation of mist of this materialmay cause respiratory tract irritation.Chronic: May cause kidney injury.Potential hazards identified with this product are those associated with the title component（Jo-1 antigen） and with following buffer and stabilising components present at concentrationsat which they are not normally considered to be hazardous:Component CAS Registry No. Concentration4-（2-Hydroxyethyl）-1-piperazineethanesulfonic acid（HEPES）7365-45-9 <0.5%Phenylmethylsulfonylfluoride 329-98-6 <0.002%Dithiothreitol 3483-12-3 <0.005%Micr-O-protect 64-17-530007-47-72612-54-30.1% AROTEC_Jo-1_MSDS.pdfVersion/Date: B/04.05.26MATERIAL SAFETY DATA SHEETProduct: , from bovine thymusSynonym: Histidyl-tRNA Synthetase / Histidine-tRNA Ligase / HISRSE.C. No.: 6.1.1.21CAS Registry No.: not availableCatalog No.: ATJ01-02, ATJ01-05, ATJ01-10*****************************************************************************************Page 2 of 3AroTec Diagnostics Limited, 10 Hutt Road, Petone, P.O. Box 38586 Wellington Mail Centre, Wellington 6332, New Zealand +64-4-5690361 ¬ +64-4-5690366 : info@arodia.comToxicological Information:Toxicological properties have not been fully investigated. May be harmful by ingestion,inhalation or skin contact. May cause allergic or autoimmune reactions.*****************************************************************************************Storage and HandlingStore according to instructions on product and/or package insert.Avoid contact with material. Wear protective equipment （protective clothing, chemicalresistant gloves, eye protection, respiratory protection） when handling.Spill or Release of Material:Wear protective equipment.Absorb liquid on dry sand, diatomite, vermiculite or other drying agent and place in closedcontainer for disposal.Ventilate area and wash spill site after material absorption is complete.Waste Disposal:Incinerate or landfill as complies with state and local laws for biological materials.*****************************************************************************************First Aid ProceduresSubstance in Contact with Skin:Remove contaminated clothing and rinse with copious amounts of soap and water for aconsiderable amount of time. Seek medical aid if irritation develops or persists.Substance has been Swallowed:If victim is conscious rinse mouth several times with water, do not swallow. Call a physician ortake victim to hospital.Substance in Contact with Eyes:Rinse with copious amounts of water for a considerable time. Seek medical aid if irritationdevelops or persists.Substance has been Inhaled:Take victim into the fresh air and allow to rest. Call a physician or take victim to hospital.Additional Instructions:Observe proper laboratory instructions when handling this material.***************************************************************************************** AROTEC_Jo-1_MSDS.pdfVersion/Date: B/04.05.26MATERIAL SAFETY DATA SHEETProduct: , from bovine thymusSynonym: Histidyl-tRNA Synthetase / Histidine-tRNA Ligase / HISRSE.C. No.: 6.1.1.21CAS Registry No.: not availableCatalog No.: ATJ01-02, ATJ01-05, ATJ01-10*****************************************************************************************Page 3 of 3AroTec Diagnostics Limited, 10 Hutt Road, Petone, P.O. Box 38586 Wellington Mail Centre, Wellington 6332, New Zealand +64-4-5690361 ¬ +64-4-5690366 : info@arodia.comFire Fighting MeasuresGeneral InformationStructural fire-fighting gear and self-contained breathing apparatus will provide adequateprotection if this product is in a fire area.Extinguishing MediaIn case of fire use water spray, dry chemical, carbon dioxide, or chemical foam.Unusual Fire and Explosion HazardsN/A*****************************************************************************************DisclaimerThe information provided in this Material Safety Data Sheet is furnished in good faith andwithout warranty of any kind. Personnel handling this material must consider these data onlyas supplemental to other information gathered by them and must make independentdeterminations of the suitability and completeness of information from all sources to assureproper use and disposal of the materials and the safety and health of employees andcustomers. AroTec Diagnostics Limited assumes no liability or responsibility resulting from theuse of, or reliance on, this information.*****************************************************************************************