pentapharm公司产品

Pentapharm总部位于瑞士Kaiseraugst 的DSM营养品公司，靠近巴塞尔，拥有日本、巴西等分支机构在内的200名员工，

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蛋白酶抑制剂

合成，低分子量丝氨酸蛋白酶抑制剂。范围包括竞争力，以及不可逆抑制剂。应用：去除不需要的蛋白水解酶活性，增加色底物检测的特异性或保护特定的蛋白质水解降解。

099-11Pefabloc®FGH-Gly-Pro-Arg-Pro-OH×AcOH099-01Inhibits fibrin polymerisation　126-05r-HirudinC287H440N80O110S6　Inhibits thrombin　380-03Pefabloc®PKC24H26N4O3S×HCl　For the determination of plasma kallikrein　381-01Pefabloc® THC27H31N5O4S×AcOH　For the determination of thrombin　381-02Pefabloc®TH1158C27H32N6O4S×HCl　For the determination of thrombin　382-03Pefabloc®uPAC32H47N5O5S×HCl　For the determination of urokinase　383-03Pefabloc®PLC31H33N5O4S2×HCl　For the determination of plasmin　384-01Pefabloc®TryC14H12N2O2×HCl×H2O　For the determination of trypsin-like　384-04Pefabloc®Try1405C26H29N5O5S×HCl　For the determination of trypsin　385-02H-Glu-Gly-Arg-CMKC14H25N6O5Cl×2TFA　For the determination of serine proteases　385-03Pefabloc®XaC20H24N4O5S×HCl　For the determination of Factor Xa　390-10Pefabloc®TrypC44H44N8O6S2×2HCl　For the determination of mast cell typtase　391-03Pefabloc®tPA/XaC23H24N4O×2HCl　For the determination of tPA/Xa　398-01Pefabloc®SPC10H10N2O3×HCl　For the determination of trypsin-like serine proteases　399-01Pefabloc®SCC8H10FNO2S×HCl　For the determination of serine proteases　800277 （1g）Aprotinin　800348 （100g）Inhibits serine proteases　

Chromogenic Substrates for Thrombin

081-01Pefachrome® TH 5244Tos-Gly-Pro-Arg-pNA ·AcOH081-03Pefachrome® THH-D-CHG-Ala-Arg-pNA · 2AcOH081-05Pefachrome® TH 5247H-D-CHG-But-Arg-pNA · 2AcOH081-08Pefachrome® TH 5250H-D-CHG-Pro-Arg-pNA · 2AcOH081-09Pefachrome® TH 5251H-D-CHA-Ala-Arg-pNA · 2AcOH081-10Pefachrome® TH 5252H-D-CHA-Gly-Arg-pNA · 2AcOH081-11Pefachrome® TH 5253H-D-CHA-Gly-Arg-pNA · 2AcOH081-15Pefachrome® TH 5256CH3OCO-Gly-Pro-Arg-pNA · AcOH081-17Pefachrome® TGH-ß-Ala-Gly-Arg-pNA · 2AcOH081-66Pefachrome® TH 8198H-D-Phe-Pip-Arg-pNA · 2HCl S-2238

Chromogenic Substrates for Factor Xa

085-01Pefachrome® FXa5277CH3SO2-D-Leu-Gly-Arg-pNA · AcOH085-03Pefachrome® FXa5279CH3OCO-D-CHG-Gly-Arg-pNA · AcOH085-05Pefachrome® FXa5112C2H5OCO-D-Val-Gly-Arg-pNA · AcOH085-06Pefachrome® FXaCH3OCO-D-CHA-Gly-Arg-pNA · AcOH085-26Pefachrome® FXa8592Cbo-Ile-Glu（γ-OR）-Gly-Arg-pNA · HCl （R=50% ME, 50% H） S-2222085-27Pefachrome® FXa8595Cbo-D-Arg-Gly-Arg-pNA · 2HCl S-2765

Chromogenic Substrates for Factor VII

093-01Pefachrome® FVIIaCH₃SO₂·-D-CHA-Abu-Arg-pNA · AcOH

Chromogenic Substrates for Factor IXa

095-01Pefachrome® FIXa3960H-D-Leu-PHG-Arg-pNA · 2AcOH

095-02Pefachrome® FIXaCH₃SO₂-D-CHG-Gly-Arg-pNA · AcOH

Chromogenic Substrates for Factor XIIa

092-02Pefachrome® FXIIaH-D-CHA-Gly-Arg-pNA · 2AcOH

Chromogenic Substrates for Urokinase

082-01Pefachrome® uPABz-ß-Ala-Gly-Arg-pNA · AcOH

082-02Pefachrome® uPA5260Cbo-Glu（OtBu）-Gly-Arg-pNA ·. AcOH

082-33Pefachrome® uPA8294pyro-Glu-Gly-Arg-pNA · 2HCl S-2444

Chromogenic Substrates for Tissue Plasminogen Activator

091-01Pefachrome® tPACH₃SO₂-D-CHA-Gly-Arg-pNA · AcOH

091-03Pefachrome® tPA5312CH₃SO₂-D-Phe-Gly-Arg-pNA · AcOH

091-05Pefachrome® tPA5314CH₃SO₂-D-Abu-Gly-Arg-pNA · AcOH

Chromogenic Substrates for Plasmin

083-01Pefachrome® PL5261Tos-Gly-Pro-Lys-pNA · AcOH

083-02Pefachrome® PL5262H-D-But-CHA-Lys-pNA · 2AcOH

083-03Pefachrome® PL5263H-D-Nva-CHA-Lys-pNA · 2AcOH

083-04Pefachrome® PL5264H-D-Nle-CHA-Lys-pNA · 2AcOH

083-09Pefachrome® PL5268H-D-Ala-CHA-Lys-pNA · 2AcOH

083-14Pefachrome® PL5272H-D-Nle-CHA-Lys-pNA · 2HCl

Chromogenic Substrates for Glandular Kallikrein

088-01Pefachrome® GKH-D-Val-CHA-Arg-pNA · 2AcOH

Chromogenic Substrates for Plasma Kallikrein

080-01Pefachrome® PK 80714Bz Pro-Phe-Arg-pNA · AcOH

080-03Pefachrome® PKH-D-Abu-CHA-Arg-pNA · 2AcOH

080-08Pefachrome® PK 8092Ca5295H-D-Pro-Phe-Arg-pNA · 2HCl S-2302

Chromogenic Substrates for Protein Ca

089-02Pefachrome® PCaH-D-Lys（Cbo）-Pro-Arg-pNA · 2AcOH

089-03Pefachrome® PCa5294H-D-CHA-Pro-Arg-pNA · 2AcOH

089-04Pefachrome® PCa5295H-D-CHA-Pro-Arg-pNA · 2AcOH

089-07Pefachrome® PCa5297Pad-Pro-Arg-pNA · AcOH

089-08Pefachrome® PCa3297Pyr-CHG-Arg-pNA · AcOH

Chromogenic Substrates for the Determination of C1-Esterase

087-01Pefachrome® C1E5292C₂H₅CO-Lys（Cbo）-Gly-Arg-pNA · AcOH

087-02Pefachrome® C1E5293CH₃OCO-Lys（Cbo）-Gly-Arg-pNA · AcOH

087-03Pefachrome® C1E 5603CH₃CO-Lys（Cbo）-Gly-Arg-pNA · AcOH

Chromogenic Substrates for Trypsin

084-01Pefachrome® TRY5274Cbo-Val-Gly-Arg-pNA · AcOH

084-03Pefachrome® TRY5276Cbo-Gly-D-Ala-Arg-pNA · AcOH

084-04Pefachrome® TRYBz-Val-Gly-Arg-pNA · AcOH

Chromogenic Substrates for the Determination of Bacterial Endotoxins

086-01Pefachrome® LAL5288CH₃OCO-D-CHA-Gly-Arg-pNA · AcOH

086-03Pefachrome® LAL5290CH₃SO₂·-D-Nle-Gly-Arg-pNA · AcOH

086-06Pefachrome® LALCH₃SO₂-D-CHA-Gly-Arg-pNA · AcOH

Other Chromogenic Substrates

083-05Pefachrome® PL-Streptplasminogen-streptokinase complex H-D-Nle-CHA-Arg-pNA · 2AcOH

090-08Pefachrome® ELAleucocyte elastase MeOSuc-Ala-Ala-Pro-Val-pNA

090-12Pefachrome® PAPpapain 3-Phenylpropionyl-Pro-Phe-Arg-pNA · AcOH

090-30Pefachrome® Colcollagenase （Clostridium histolyticum） Cbo-Gly-Pro-Leu-Gly-Pro-pNA

090-35Pefachrome® TrypTryptase, Plasmin Tos-Gly-Pro-Lys-pNA · AcOH

Fluorogenic Substrates for Thrombin

081-19Pefafluor® THH-D-CHA-Ala-Arg-AMC · 2AcOH

082-03Pefafluor® uPABz-ß-Ala-Gly-Arg-AMC · AcOH

085-12Pefafluor® FXaCH₃SO₂-D-CHA-Gly-Arg-AMC · AcOH

086-04Pefafluor® LAL5291CH₃SO₂·-D-CHA-Gly-Arg-AMC · AcOH

089-05Pefafluor® PCaPyr-Pro-Arg-AMC · AcOH

089-10Pefafluor® PCa3342Pyr-CHG-Arg-AMC · AcOH

082-03Pefafluor® uPABz-ß-Ala-Gly-Arg-AMC · AcOH

091-06Pefafluor® tPACH₃SO₂-D-Phe-Gly-Arg-AMC · AcOH

800049Pefafluor® MMP-2 Abz-Lys-Leu-Pro-Ala-Nva-Glu（pNA）-Ala-Arg-NH2 • 3TFAMatrix metalloproteinase 2

800050Pefafluor® MMP-7 Abz-Lys-Pro-Leu-Glu-Leu-Glu（pNA）-Ala Arg-NH2 • 3TFAMatrix metalloproteinase 7

081-19Pefafluor® THH-D-CHA-Ala-Arg-AMC · 2AcOH

Snake Venom Proteins

ActivatorSourceApplicationRemarks113-01 / 113-04Protac®• Determination of protein C and protein S• Protein C pathway assaysSerine protease Agkistrodon contortrix

116-01Ecarin• Prothrombin assay• Determination of hirudinMetalloprotease, activates specifically prothrombin via meizothrombin, does not need PL and Ca2+ Echis carinatus

119-02ConvulxinActivation of human plaets via binding and clustering of GPVI-receptors under physiological conditionsCrotalus durissus

121-03RVV Factor V-ActivatorActivation of FV in APC-R assaySerine protease, not inhibited by AT

121-06RVV-X• Determination of FX• Screening assay for lupus anti-coagulants （diluted Russel viper venom test, dRVVT）Metalloprotease, does also （weakly） activate protein C and factor IX Daboia （Vipera） russelli

800191Pefakit® Reptilase® TimeReady-to-use diagnostic reagent for measurement of• functionality of fibrin poly-merisation• afibrinogenemia or hypofibrinogen-emia• hyperfibrinolysis• thrombolytic therapyCE-marked IVD Bothrops atrox

069-03Prionex® （sterile hydrolyzed gelatine）Protein stabilization116-10HEPES-bufferEcarin148-03Gelatine 10% （solution）Protein stabilization801682Rabbit Brain CephalinPhospholipid source

Pefakit® APC-R Factor V

FlyerPefakit® APC-R Factor V LeidenPefakit® APC-R Factor V Leiden is a plasma based functional assay for the determination of resistance of Factor Va to inactivation by activated protein C （APC） caused by the factor V Leiden mutation （FV:Q506）Pack:3 x 2 mlAPC /RVV-V （+APC） Reagent3 x 2 mlRVV-V （-APC） Reagent3 x 4 mlPTA Reagent3 x 2 mlDilution PlasmaREF:502-01Pefakit® APC-R Factor V Leiden ControlsControl plasmas for confirmation of factor V Leiden mutation （FV:Q） in assays for determination of the functional phenotype for activated protein C resistance caused by the factor V Leiden mutation.Pack:3 x 1 mlFV-L Negative Control3 x 1 mlFV-L Heterozygous ControlREF:502-21Pefakit® APC-R Factor V Leiden Homozygous ControlControl plasma for confirmation of factor V Leiden mutation （FV:Q） in assays for determination of the functional phenotype for activated protein C resistance caused by the factor V Leiden mutation.Pack:3 x 0.5 mlFV-L Homozygous ControlREF:502-23

Pefakit® Reptilase®Time

Pefakit® Reptilase®TimeFor the investigation of the last phase of blood coagulation. Due to its heparin insensitivity the Reptilase®Time can detect fibrinogen polymerization disorders even in the presence of heparin.Pack:3 x 1 mlReptilase®Time ReagentREF:800191

Pefakit® in-TDT

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Pefakit® in-TDT

Determination of initial thrombin formation by intrinsic activation.

Pack: 2 x 2 ml Reagent

2 x 2 ml Activator

2 x 2,5 ml Diluent

1 x 1 ml Calibrator

1 x 1 ml Control N

1 x 1 ml Control P

REF: 800236

You can order your free manual and adaption protocol by clicking on the contact option on top of the screen.- Manual for the Analysis Software Tool BCS®- BCS Adaption protocol for Pefakit® in-TDT® Art. 800236- Manual for the Analysis Software Tool ACL 9000- ACL-9000 Adaption protocol for Pefakit® in-TDT® Art. 800236

Pefakit® PiCT®

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Pefakit® PiCT®- Prothrombinase induced Clotting Time

Pefakit® PiCT® is a plasma based functional assay for the determination of factor Xa and factor IIa inhibitors.Pack:3 x 2 mlPiCT® Activator3 x 2 mlPiCT® Start ReagentREF:505-01Applications for various haemostasis systems on requestApplications for direct factor Xa inhibitors on requestPefakit® PiCT® Calibrators UFHPack:3 x 1 mlUFH Calibrator 13 x 1 mlUFH Calibrator 2REF:505-121Pefakit® PiCT® Controls UFHPack:3 x 1 mlUFH Control 13 x 1 mlUFH Control 2REF:505-22Pefakit® PiCT® Calibrators LMWHPack:3 x 1 mlLMWH Calibrator 13 x 1 mlLMWH Calibrator 2REF:505-11Pefakit® PiCT® Controls LMWHPack:3 x 1 mlLMWH Control 13 x 1 mlLMWH Control 2REF:505-21Pefakit® PiCT® Calibrators HirudinPack:3 x 1 mlHirudin Calibrator 13 x 1 mlHirudin Calibrator 2REF:505-13Pefakit® PiCT® Controls HirudinPack:3 x 1 mlHirudin Controls 13 x 1 mlHirudin Controls 2REF:505-23

Pefakit® TAFI