货号：AB1587P

品牌：Merck Millipore

规格：50Ug

目录价：￥6742.00

市场价格：￥5730.70

会员价格：￥5393.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Adenosine A1 Receptor Antibody | AB1587P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Adenosine A1 receptor (A1R). Recognizes the 79 kDa and 39 kDa bands of in cortical membranes from rat, porcine and lamb. The 79 kDa band can be converted to 39 kDa band by agonist or antagonist treatment and could represent a A1R dimers. View All» Molecular Weight: 79 kDa and 39 kDa View All» Immunogen: Amino acid sequence corresponding to the 3rd extracellular domain (amino acids 163-176, GEPVIKCEFEKVIS) of the rat A1R gene. View All» Species Reactivity:

• Guinea Pig

• Human

• Pig

• Rat

• Sheep
  View All» Application Notes: Immunohistochemistry: 10-50 μg/mL on frozen tissue sections. Light fixation is recommended. 2% 0.2% picric acid {Cooke, HJ (1999) AJP Gastrointest Liver Physiol 276:4516-4626} Immunocytochemistry: Caufield, 2003. Light 2% PFA fixation 5-10 minutes --long fixations lower staining intensity. Western blot: 1-10 μg/mL (Chemiluminescence technique): Membrane preparations are recommended for enhanced signals {Smith et al (2001) Biochem Pharmacology 61:237-244} Higher concentrations of the antibody may be necessary if calorimetric detection or milk-based antibody diluent are used. ELISA: 1:10,000-1:50,000 (50-100 ng A1R peptide (Cat. Number AG289)/well) Optimal working dilutions must be determined by end user. View All» Control: Brain tissue View All» Purification Method: Immunoaffinity purified View All» Presentation: Affinity Purified immunoglobulin. Liquid in PBS with 0.1% BSA. View All» Storage Conditions: Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P30542 View All» Entrez Gene Number:
  • NM_000674.2

  • NM_001048230.1
    View All» Gene Symbol:
    • ADORA1

    • RDC7
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • ELISA

      • Immunocytochemistry

      • Immunohistochemistry

      • Western Blotting
        View All» Entrez Gene Summary: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P30542 # Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.SIZE: 326 amino acids; 36512 Da SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.SIMILARITY: SwissProt: P30542 ## Belongs to the G-protein coupled receptor 1 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Adenosine A1 Receptor Antibody | AB1587P View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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