货号：17-176

品牌：Merck Millipore

规格：

目录价：￥6739.00

市场价格：￥5728.15

会员价格：￥5391.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: STATPAK, Anti-STAT (1, 2, 3, 5A, 5B) Miniature Set View All» Promotional Text: Special Offer on Antibodies! Click Here! View All» Trade Name: Upstate (Millipore) View All» Species Reactivity:

• Human

• Mouse
  View All» Quality Assurance: routinely evaluated in western blot, immunoprecipitation, EMSA or immunocytochemistry View All» UniProt Number:
  • P42224

  • P52630

  • P40763

  • P42229

  • P51692
    View All» Entrez Gene Number:
    • NM_007315.2

    • NM_139266.1
      View All» Gene Symbol:
      • STAT1

      • ISGF-3

      • STAT91

      • DKFZp686B04100
        View All» Components:
        • Anti-STAT1, Catalog #06-501-MN

        • Anti-STAT2, Catalog #06-502-MN

        • Anti-STAT3, Catalog #06-596-MN

        • Anti-STAT5A, Catalog #06-553-MN

        • Anti-STAT5B, Catalog #06-554-MN
          View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
          • Electrophoretic Mobility Shift Assay

          • Immunoprecipitation

          • Western Blotting

          • Immunocytochemistry
            View All» Entrez Gene Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. View All» UniProt Summary: FUNCTION: SwissProt: P51692 # Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.SIZE: 787 amino acids; 89866 Da SUBUNIT: Forms a homodimer or a heterodimer with a related family member. Binds NR3C1 (By similarity). Interacts with NCOA1, NMI and SOCS7.SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By similarity). Note=Translocated into the nucleus in response to phosphorylation (By similarity).PTM: Tyrosine phosphorylated (By similarity).DISEASE: SwissProt: P51692 # Defects in STAT5B are the cause of Laron type dwarfism II (LTD2) [MIM:245590]; also known as Laron syndrome type II or Laron syndrome due to a post-receptor defect. The phenotypic features are consistent with growth hormone deficiency in the presence of normal to elevated circulating concentrations of growth hormone, and resistance to hexogeneous hormone therapy.SIMILARITY: SwissProt: P51692 ## Belongs to the transcription factor STAT family. & Contains 1 SH2 domain. View All» Brand Family: Upstate View All» Product Name: STATPAK, Anti-STAT (1, 2, 3, 5A, 5B) Miniature Set View All» Qty/Pk: 1 kit View All» Host: Rabbit View All»
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            © Merck Millipore代理17-176 STATPAK Miniature Set (Anti-STAT1, 2, 3, 5A, 5B)，产品报价联系微信jinshanbio