R&D Systems代理929-ZN-010 Recombinant Human ACE Protein, CF (10 UG)

2025-07-22

货号:929-ZN-010

品牌:R&D Systems

规格:10ug

目录价:¥4490.00

市场价格:¥3592.00

会员价格:¥3592.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Source:Mouse myeloma cell line, NS0-derived, Leu30-Leu1261, with a C-terminal 10-His tag Accession #:P12821.1 N-terminal Sequence Analysis:Leu30 Structure:Recombinant Human ACE/CD143SomaticForm is prone to proteolytic cleavage at C-terminus. The predominant form of the purified protein lacks the His tag. Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:143 kDa SDS-PAGE:160-180kDa, reducing conditions Activity:Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPPGFSAFK(Dnp)-OH (Catalog# ES005).The specific activity is >1,000pmol/min/µg, as measured under the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in Tris, NaCl, ZnCl2 and Glycerol.See Certificate of Analysis for details. Molecule Information: ACE/CD143 Long Name: Angiotensin I Converting Enzyme Aliases: CD143; DCP1; Kininase II Entrez Gene IDs: 1636 (Human); 11421 (Mouse) Background: ACE

    View ACE IHC images. ACE and ACE-2, two cell surface proteases, are important regulators of the renin-angiotensin system (RAS), which plays a key role in maintaining blood pressure homeostasis and fluid salt balance in mammals. Because of its location and specificity, ACE plays additional roles in immunity, reproduction and neuropeptide regulation. ACE exists in two isoforms. Somatic ACE comprises two highly similar protease domains whereas germinal ACE comprises a single protease domain. ACE-2 consists of a single protease domain and is an essential regulator of heart and lung function. It is also a cellular receptor for the Spike protein of SARS cornonavirus that causes severe acute respiratory syndrome.

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