金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Ala22-Gln421, with a C-terminal 10-His tag Accession #:NP_001025462 N-terminal Sequence Analysis:Ala22 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:47 kDa SDS-PAGE:60 kDa, reducing conditions Activity:Measured by its ability to hydrolyze sphingomyelin to ceramide and phosphorylcholine. The phosphorylcholine is cleaved by Recombinant Human AlkalinePhosphatase/ALPL (Catalog# 2909-AP) and the phosphate is detected/measured by a Malachite Green Phosphate Detection Kit (Catalog# DY996).The specific activity is >13,000 pmol/min/µg, as measured under the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in Tris and NaCl.See Certificate of Analysis for details. Molecule Information: ENPP-7/Alk-SMase Long Name: Ectonucleotide Pyrophosphatase/Phosphodiesterase 7 Aliases: Alk-SMase Entrez Gene IDs: 339221 (Human); 238011 (Mouse); 303729 (Rat) Background: ENPP-7/Alk-SMase ENPP-7 (ectonucleotide pyrophosphatase/phosphodiesterase 7), also known as alkaline sphingomyelinase (alk-SMase) is a 60 kDa GPI-linked membrane glycoprotein expressed in the intestines and in human bile. It shares 30% - 36% homology with the NPP family, but is unrelated to neutral or acid SMase. ENPP-7 hydrolyzes dietary sphingomyelin to form ceramide and phosphorylcholine, and may also hydrolyze and inactivate platelet-activating factor (PAF). It is downregulated in some human colorectal carcinomas.