货号：07-410

品牌：Merck Millipore

规格：200UL

目录价：￥5265.00

市场价格：￥4475.25

会员价格：￥4212.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-WAVE2/Scar2 Antibody | 07-410 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: WAVE2/Scar2 View All» Molecular Weight: ~68kDa View All» Immunogen: peptide corresponding to amino acids 186-200 of human WAVE2/Scar2, with an N-terminal cysteine View All» Isotype: IgG View All» Species Reactivity:

• Human

• Rat
  View All» Quality Assurance: routinely evaluated by immunoblot in in RIPA lysates from HL60 cells View All» Purification Method: Antiserum View All» Presentation: 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: Q9Y6W5 View All» Entrez Gene Number: NM_006990 View All» Gene Symbol:
  • WASF2

  • WAVE2

  • IMD2

  • SCAR2

  • dJ393P12.2
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. View All» UniProt Summary: FUNCTION: SwissProt: Q9Y6W5 # Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton.SIZE: 498 amino acids; 54284 Da SUBUNIT: Binds actin and the Arp2/3 complex. Interacts with BAIAP2. Component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 and WASF2/WAVE2. Directly interacts with C3orf10/HSPC300.SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton (By similarity). Cell projection, lamellipodium (By similarity). Note=At the interface between the lamellipodial actin meshwork and the membrane (By similarity).TISSUE SPECIFICITY: Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle.DOMAIN:SwissProt: Q9Y6W5 Binds the Arp2/3 complex through the C-terminal region and actin through verprolin homology (VPH) domain.SIMILARITY: Contains 1 WH2 domain. View All» Brand Family: Upstate View All» Product Name: Anti-WAVE2/Scar2 Antibody | 07-410 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µL View All» Format: Serum View All» Host: Rabbit View All»
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