Merck Millipore代理06-691 Anti-Caspase 6 (Mch2)

2025-07-23

货号:06-691

品牌:Merck Millipore

规格:

目录价:¥4154.00

市场价格:¥3530.90

会员价格:¥3323.20

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Caspase 6 Antibody | 06-691 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Caspase 6 View All» Molecular Weight: 34kDa View All» Immunogen: peptide [CEENMTETDAFYKREMFD] corresponding to amino acids 16-32 of human Caspase 6 View All» Isotype: IgG View All» Species Reactivity: Human View All» Quality Assurance: routinely evaluated by immunoblot on RIPA lysates from Jurkat cells View All» Purification Method: Protein A chromatography View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P55212 View All» Entrez Gene Number: NM_032992 View All» Gene Symbol:

  • CASP6

  • CASP-6

  • MCH2

    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting

      View All» Entrez Gene Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. View All» UniProt Summary: FUNCTION: SwissProt: P55212 # Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.SIZE: 293 amino acids; 33310 Da SUBUNIT: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit.SUBCELLULAR LOCATION: Cytoplasm.PTM: Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.SIMILARITY: SwissProt: P55212 ## Belongs to the peptidase C14 family. View All» Brand Family: Upstate View All» Product Name: Anti-Caspase 6 Antibody | 06-691 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Rabbit View All»

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