货号：06-1076

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-IL-22 Antibody | 06-1076 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes IL-22 near the C-terminus. This antibody was also used on ELISA to test specificity against the immunizing peptide. View All» Molecular Weight: ~17 kDa View All» Epitope: Near C-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to human IL-22 around the C-terminus. View All» Background Information: Interleukin 22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. It is produced by normal T cells upon CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF29) and IL10Rβ (previously known as CRF24), belonging to the class II cytokine receptor family. View All» Species Reactivity:

• Human

• Monkey
  View All» Species Reactivity Note: Proven to react with human. Predicted to react with monkey based on 100% sequence homology. View All» Application Notes: Immunohistochemistry Analysis: A 1:100 dilution from a previous lot detected IL-22 in human tonsil tissue.Flow Cytometry Analysis: 5 µg from a previous lot detected IL-22 in lymphocytes from human PBMC's. View All» Control: Recombinant Human IL-22 lysate View All» Quality Assurance: Evaluated by Western Blot on recombinant human IL-22 lysate.Western Blot Analysis: 1:5,000 dilution of this antibody detected IL-22 on 10 µg of recombinant human IL-22 lysate. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit polyclonal in PBS with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9GZX6 View All» Entrez Gene Number: NP_065386 View All» Gene Symbol:
  • IL22

  • IL-21

  • IL-22

  • IL-D110

  • IL-TIF

  • IL21

  • ILTIF

  • TIFIL-23

  • TIFa

  • zcyto18
    View All» Alternate Names:
    • IL-10-related T-cell-derived inducible factor

    • IL-10-related T-cell-derived-inducible factor

    • interleukin 21

    • interleukin 22
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry

      • Flow Cytometry
        View All» UniProt Summary: FUNCTION: Cytokine that contributes to the inflammatory response in vivo.SUBCELLULAR LOCATION: Secreted. SEQUENCE SIMILARITIES: Belongs to the IL-10 family. View All» Product Name: Anti-IL-22 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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