Merck Millipore代理MABC260 Anti-TRAF1 Antibody, clone 1F3;store at +2℃ to +8℃

2025-07-24

货号:MABC260

品牌:Merck Millipore

规格:100UL

目录价:¥5666.00

市场价格:¥4816.10

会员价格:¥4532.80

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-TRAF1 Antibody, clone 1F3 | Cat. No. MABC260 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~46 kDa observed. Uniprot describes an isoform produced by alternative splicing at ~33 kDa. View All» Immunogen: GST-tagged recombinant protein corresponding to human TRAF1. View All» Clone: 1F3 View All» Isotype: IgG2aκ View All» Background Information: TNF receptor-associated factor 1 (TRAF1), also known as Epstein-Barr virus-induced protein 6 (EBI6), is an adapter protein belonging to the TRAF family. It contains the conserved C-terminal TRAF domain that is required for trimerization and interaction with cell surface receptors such as CD30, CD40, OX40, AITR, and RANK. TRAF1 also interacts with a variety of cytoplasmic proteins such as RIP1, RIP2, A20 and TRIP. Among other functions, TRAF1 is involved in regulating NF-kB and JNK signaling. TRAF1 is expressed in the lung, testis, and spleen, and can be induced by TNF-α, interleukin (IL)-1 or EBV infection. Previous studies have suggested that TRAF1 may play a role in oncogenesis. View All» Species Reactivity:

  • Monkey

  • Human

    View All» Species Reactivity Note: Demonstrated to react with Human and Monkey. Predicted to react with Human based on immunogen design. View All» Application Notes: Immunohistochemistry Analysis: A representative lot was used by an an independent laboratory to detect TRAF1 in certain cell lines (Siegler, G., et al. (2003). J Clin Pathol: Mol Pathol. 56:156-161.). Flow Cytometry Analysis: A representative lot was used by an an independent laboratory to detect TRAF1 in PBMCs and in certain T cells from HIV-infected individuals (Wang, C., et al. (2011). JEM.1-15.). View All» Control: B95-8cell lysate View All» Quality Assurance: Evaluated by Western Blot in B95-8 cell lysate.Western Blot Analysis: A 1:1,000 dilution of this antibody detected TRAF1 in 10 µg of B95-8cell lysate. View All» Purification Method: Protein G purified View All» Presentation: Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q13077 View All» Entrez Gene Number: NP_001177874 View All» Gene Symbol:
    • TRAF1

    • EBI6

      View All» Alternate Names:
      • TNF receptor-associated factor 1

      • TNF receptor-associated factor 1

        View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
        • Western Blotting

        • Immunohistochemistry

        • Flow Cytometry

          View All» Product Name: Anti-TRAF1, clone 1F3 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Rat View All»

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