货号:MABC260
品牌:Merck Millipore
规格:100UL
目录价:¥5666.00
市场价格:¥4816.10
会员价格:¥4532.80
金山科研平台,产品价格货期咨询微信:jinshanbio
Description:
Anti-TRAF1 Antibody, clone 1F3 | Cat. No. MABC260
View All»
Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
View All»
Molecular Weight:
~46 kDa observed. Uniprot describes an isoform produced by alternative splicing at ~33 kDa.
View All»
Immunogen:
GST-tagged recombinant protein corresponding to human TRAF1.
View All»
Clone:
1F3
View All»
Isotype:
IgG2aκ
View All»
Background Information:
TNF receptor-associated factor 1 (TRAF1), also known as Epstein-Barr virus-induced protein 6 (EBI6), is an adapter protein belonging to the TRAF family. It contains the conserved C-terminal TRAF domain that is required for trimerization and interaction with cell surface receptors such as CD30, CD40, OX40, AITR, and RANK. TRAF1 also interacts with a variety of cytoplasmic proteins such as RIP1, RIP2, A20 and TRIP. Among other functions, TRAF1 is involved in regulating NF-kB and JNK signaling. TRAF1 is expressed in the lung, testis, and spleen, and can be induced by TNF-α, interleukin (IL)-1 or EBV infection. Previous studies have suggested that TRAF1 may play a role in oncogenesis.
View All»
Species Reactivity:
-
Monkey
-
Human
View All»
Species Reactivity Note:
Demonstrated to react with Human and Monkey. Predicted to react with Human based on immunogen design.
View All»
Application Notes:
Immunohistochemistry Analysis: A representative lot was used by an an independent laboratory to detect TRAF1 in certain cell lines (Siegler, G., et al. (2003). J Clin Pathol: Mol Pathol. 56:156-161.). Flow Cytometry Analysis: A representative lot was used by an an independent laboratory to detect TRAF1 in PBMCs and in certain T cells from HIV-infected individuals (Wang, C., et al. (2011). JEM.1-15.).
View All»
Control:
B95-8cell lysate
View All»
Quality Assurance:
Evaluated by Western Blot in B95-8 cell lysate.Western Blot Analysis: A 1:1,000 dilution of this antibody detected TRAF1 in 10 µg of B95-8cell lysate.
View All»
Purification Method:
Protein G purified
View All»
Presentation:
Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
View All»
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
View All»
UniProt Number:
Q13077
View All»
Entrez Gene Number:
NP_001177874
View All»
Gene Symbol:
-
TRAF1
-
EBI6
View All»
Alternate Names:
-
TNF receptor-associated factor 1
-
TNF receptor-associated factor 1
View All»
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
View All»
Key Applications:
-
Western Blotting
-
Immunohistochemistry
-
Flow Cytometry
View All»
Product Name:
Anti-TRAF1, clone 1F3
View All»
Antibody Type:
Monoclonal Antibody
View All»
Qty/Pk:
100 µL
View All»
Format:
Purified
View All»
Host:
Rat
View All»
©
金山科研平台是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:
http://16ao.com/thread-132829.htm
© Merck Millipore代理MABC260 Anti-TRAF1 Antibody, clone 1F3;store at +2℃ to +8℃,产品报价联系微信jinshanbio
特别声明:以上内容(如有图片亦包括在内)来源于授权厂家或网络,如有侵权,请联系删除,本平台不提供信息存储服务。
Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.