货号：341148

品牌：BD IS

规格：50T

目录价：￥8915.00

市场价格：￥6240.50

会员价格：￥5794.75

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More than 50% of the peripheral B lymphocytes of normal adults carry FMC7 antigen at variable density. FMC7-positive B cells are more mature and they are the subpopulation that responds in vitro to mitogens or antigens. The FMC7 antigen is found on B-cell malignancies of most differentiated stages, such as mantle cell lymphoma (MCL), follicular lymphoma, and hairy-cell leukemias, but not in most cases of chronic lymphocytic leukemia (CLL).The CD23 antigen is present at low density on most normal B lymphocytes and at higher levels on activated B lymphocytes, Epstein-Barr virus (EBV)-transformed lymphoblasts, CLL cells of B-lymphocyte origin, and tonsillar B lymphocytes.CD23 antigen density increases on the surface of B lymphocytes shortly after activation. The antigen is lost after isotype switching to IgA, IgG, or IgE. The CD23 antigen is not present on immature bone marrow B lymphocytes or on T lymphocytes, but it has been reported on monocytes, hypodense eosinophils, and a subpopulation of platelets.The CD19 antigen is present on approximately 7-23% of human peripheral blood lymphocytes and on splenocytes. The CD19 antigen is present on human B lymphocytes at all stages of maturation. CD19 does not react with resting or activated T lymphocytes, granulocytes, or monocytes.

Catalog Number

341148

Brand

BD Oncomark™

Name

FMC7/CD23/CD19

Size

50Tests

RegulatoryStatus

RUO (GMP)