货号：550605

品牌：BD Pharmingen

规格：500ug

目录价：￥7831.00

市场价格：￥4933.53

会员价格：￥4307.05

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Purified antibody in 10 mM sodium phosphate, pH 7.2, with 150 mM NaCl and 0.09% (w/v) sodium azide.

Preparation and Storage

Preparation: The B122 antibody was purified from tissue culture supernatant via Protein G column chromatography. Storage: The antibody solution should be stored undiluted at 4°C.

Caution

Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Conditions

The information disclosed herein is not to be construed as a recommendation to use the above product in violation of any patents. BD PharMingen will not be held responsible for patent infringement or other violations that may occur with the use of our products.

Catalog Number

550605

Brand

BD Pharmingen™

Name

IL-1β

Concentration

0.5 mg/ml

Size

0.5mg

RegulatoryStatus

RUO

Clone

B122

Format

Purified

Isotype

IgG₁, λ1

W.B. Positive Control

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Immunogen

Mouse IL-1β Protein

Reactivity

QC Testing : Mouse

Applications

ELISA Capture	- Routinely Tested
Immunoprecipitation/Western Blot	- Reported
Neutralization	- Tested During Development

Clone - References

1. Hogquist, K. A., M. A. Nett, K. C. Sheehan, K. D. Pendleton, R. D. Schreiber, and D. D. Chaplin. 1991. Generation of monoclonal antibodies to murine IL-1b and demonstration of IL-1 in vivo. J. Immunol. 146:1534 – 1540.2. Miller, B. E., P. A. Krasney, D. M. Gauvin, K. B. Holbrook, D. J. Koonz, R. V. Abruzzese, R. E. Miller, K. A. Pagani, R. E. Dolle, M. A. Ator, and S. C. Gilman. 1995. Inhibition of mature IL-1b production in murine macrophages and a murine model of inflammation by WIN 67694, an inhibitor of IL-1b converting enzyme. J. Immunol. 154:1331-1338.3. Wu, X., A. J. Wittwer, L. S. Carr, B. A. Crippes, J. E. DeLarco, and J. B. Lefkowith. 1994. Cytokine-induced neutrophil chemoattractant mediates neutrophil influx in immune complex glomerulonephritis in rat. J. Clin. Invest. 94:337 - 344.4. Troy, C. M., L. Stefanis, A. Prochiantz, L. A. Greene, and M. L. Shelanski. 1996. The contrasting roles of ICE family proteases and interleukin-1beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation. Proc. Natl. Acad. Sci. USA 93:5635 - 5640.5. Fei, R., K. Gott, B. Edwards, and M. Schuyler. 1995. Experimental hypersensitivity pneumonitis: in vitro effects of interleukin-2 and interferon-gamma. J. Lab. Clin. Med. 126:485 - 494.