货号：550543

品牌：BD Pharmingen

规格：1EA

目录价：￥3512.00

市场价格：￥2212.56

会员价格：￥1931.60

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Purified immunoglobulin in IHC antibody diluent containing serum* and 0.09% (w/v) sodium azide.

Preparation and Storage

Preparation: The antibody is purified from tissue culture supernatant by Protein G affinity chromatographyStorage: Store at 4°C.

Caution

Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Conditions

The information disclosed herein is not to be construed as a recommendation to use the above product in violation of any patents. PharMingen will not be held responsible for patent infringement or other violations that may occur with the use of our products.

Catalog Number

550543

Brand

BD Pharmingen™

Name

CD90.2

Alias

Thy-1.2

Concentration

62.5 µg/ml

Size

1mL

RegulatoryStatus

RUO

Clone

53-2.1

Format

Purified

Isotype

IgG_2a, κ

W.B. Positive Control

none

Immunogen

Mouse Thymus / Spleen

Strain Host

LOU

Reactivity

QC Testing : Mouse

Applications

Flow cytometry	- Routinely Tested
Immunohistochemistry-formalin (antigen retrieval required)	- Not Recommended
Immunohistochemistry-frozen	- Tested During Development

Clone - References

1. Ledbetter, J.A., and L.A. Herzenberg. 1979. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol. Rev. 47: 63 - 90.2. Ledbetter, J.A., R.V. Rouse, H.S. Micklem, and L.A. Herzenberg. 1980. T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views. J. Exp. Med. 152: 280 - 295.3. Zheng, B., S. Han, and G. Kelsoe. 1996. T helper cells in murine germinal centers are antigen-specific emigrants that downregulate Thy-1. J. Exp. Med. 184: 1083 - 1091.4. Zhong, R.-k., A.D. Donnenberg, L. Edison, and D.E. Harrison. 1996. The appearance of Thy-1- donor T cells in the peripheral circulation 3-6 weeks after bone marrow transplantation suggests an extrathymic origin. Int. Immunol. 8: 171 - 176.5. Tigelaar, R.E., J.M. Lewis, and P.R. Bergstresser. 1990. TCR g/d+ dendritic epidermal T cells as constituents of skin-associated lymphoid tissue. J. Invest. Dermatol. 94: 58S - 63S.6. Lefranois, L. 1991. Extrathymic differentiation of intraepithelial lymphocytes: generation of a separate and unequal T-cell repertoire? Immunol. Today 12: 436 - 438.7. Phipps, R.P., D.P. Penney, P. Keng, H. Quill, A. Paxhia, S. Derdak, and M.E. Felch. 1989. Characterization of two major populations of lung fibroblasts: Distinguishing morphology and discordant display of Thy 1 and Class II MHC. Am. J. Respir. Cell Mol. Biol. 1: 65 - 74.8. Radrizzani, M., H. Carminatti, O.H. Pivetta, and V.P.I. Vargas. 1995. Developmental regulation of Thy 1.2 rate of synthesis in the mouse cerebellum. J. Neurosci. Res. 42: 220 - 227.9. Ikuta, K., N. Uchida, J. Friedman, and I.L. Weissman. 1992. Lymphocyte development from stem cells. Annu. Rev. Immunol. 10: 759 - 783.10. Williams, A.F., and J. Gagnon. 1982. Neuronal cell Thy-1 glycoprotein: Homology with immunoglobulin. Science 216: 696 - 703.11. Kroczek, R.A., K.C. Gunter, R.N. Germain, and E.M. Shevach. 1986. Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes. Nature 322: 181 - 184.12. Hueber, A.-O., G. Raposo, M. Pierres, and H.-T. He. 1994. Thy-1 triggers mouse thymocyte apoptosis through a bcl-2-resistant mechanism. J. Exp. Med. 179: 785 - 796.13. He, H.-T., P. Naquet, D. Caillol, and M. Pierres. 1991. Thy-1 supports adhesion of mouse thymocytes to thymic epithelial cells through a CA²⁺ independent mechanism. J. Exp. Med. 173: 515 - 518.

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