货号：550428

品牌：BD Pharmingen

规格：1EA

目录价：￥5770.00

市场价格：￥3635.10

会员价格：￥3173.50

金山科研平台，产品价格货期咨询微信：jinshanbio

Catalog Number

550428

Brand

BD Pharmingen™

Name

IRF-3

Concentration

0.5 mg/ml

Size

50µg

RegulatoryStatus

RUO

Clone

SL-12.1

Format

Purified

Isotype

IgG₁

W.B. Positive Control

Jurkat

Molecular Weight

50 kDa

Immunogen

Human IRF-3 aa. 56-427 recombinant fusion protein

Reactivity

QC Testing : Human

Applications

Blocking	- Reported
Immunofluorescence	- Reported
Immunoprecipitation	- Reported
Western Blot	- Routinely Tested

Clone - References

Reich, N., B. Evans, D.E. Levy, D. Fahey, E. Knight, and J.E. Darnell Jr. 1987. Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc. Natl. Acad. Sci. USA 84:6394-6398.Loh, J.E., C-H. Chang, W.L. Foder, and R.A. Flavell. 1992. Dissection of the interferon gamma-MHC class II signal transduction pathway reveals that type I and type II interferon systems share common signalling component(s). EMBO J. 11Mamane, Y., C. Heylbroeck, P. Genin, M. Algarte, M.J. Servant, C. LePage, C. DeLuca, H. Kwon, R. Lin, and J. Hiscott. 1999. Interferon regulatory factors: the next generation. Gene 237:1-14.Darnell, J.E., I.M. Kerr, and G.R. Starck. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415-1421.Au, W-C., P.A. Moore, W. Lowther, Y-T. Juang, and P.M. Pitha. 1995. Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induceHiscott, J., P. Pitha, P. Genin, H. Nguyen, C. Heylbroeck, Y. Mamane, M. Algarte, and R. Lin. 1999. Triggering the interferon response: the role of IRF-3 transcription factor. J. Interferon Cytokine Res. 19:1-13.Wathelet, M.G., C.H. Lin, B.S. Parekh, L.V. Ronco, P.M. Howley, and T. Maniatis. 1998. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-b enhancer in vivo. Mol. CellRonco, L.V., A.Y. Karpova, M. Vidal, and P.M. Howley. 1998. Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity. Genes & Dev. 12:2061-2072.