GK104 ScienCell 人类细胞骨架重塑qPCR检测试剂盒，Human Cytoskeletal Remodeling qPCR Array Kit

ScienCell 研究实验室（ScienCell）是一家生物技术公司，其使命是实验和治疗用细胞和细胞科研金山平台现货促销授权一级代理，咨询微信：jinshanbio 金山禾斗石开平台总代理的研究和发展。 ScienCell为研究界提供各种高质量的正常的人类和动物细胞，细胞培养基和试剂，培养基添加因子，细胞来源的RNA，cDNA和蛋白质。ScienCell的科学家们以改善生活质量，实现细胞的能力，打击人类退化性疾病为目的研究和开发各种细胞治疗策略。ScienCell总部设在美国加利福尼亚州圣地亚哥，公司成立于1999年。

北京诺博莱德作为ScienCell品牌的特约代理商，为客户提供，正规进口，保证原装正品，货期稳定，折扣好的服务标准。

GK104 ScienCell人类细胞骨架重塑qPCR检测试剂盒，Human Cytoskeletal Remodeling qPCR Array Kit，产品简介：

产品品牌： ScienCell

产品货号：GK104

产品名称：GK104 ScienCell人类细胞骨架重塑qPCR检测试剂盒，Human Cytoskeletal Remodeling qPCR Array Kit

产品规格：One 96-well plate, one 20ul reaction per well

GK104 ScienCell人类细胞骨架重塑qPCR检测试剂盒，Human Cytoskeletal Remodeling qPCR Array Kit， 产品说明：

ScienCell的GeneQuery™人类细胞骨架重塑qPCR阵列试剂盒（GQH-CYT）分析了参与细胞骨架重塑的88个关键基因，特别关注Rho GTP酶肌动蛋白细胞骨架重塑。 细胞骨架负责维持细胞形状、支架和调节细胞内运输。 它还参与许多信号通路、细胞分裂、囊泡运输和运动。 微丝主要是肌动蛋白聚合物，是细胞骨架的一部分，由GTP酶Rho家族调节。 如何对所包含的基因进行分类的简要示例如下所示：

细胞骨架成分：ACTA1、ACTB、ACTG1、ACTN1、MYH10、MYL1

整合素： ITGA1， ITGA3， ITGAV， ITGB1， ITGB3

细胞外基质成分：COL1A1，COL2A1，COL4A1，LAMA1，LAMB1

Rho信号分子：CAV1，CDC42，RAC1，RHOA，ROCK1，ROCK2

转录因子：CDX1、CDX2、SP1、TCF7、TCF7L1

GeneQuery™ qPCR 芯片试剂盒采用 96 孔板格式的 qPCR 就绪，每个孔包含一个引物组，可识别并有效扩增特定靶基因的 cDNA。精心设计的引物确保：（i）qPCR分析中的最佳退火温度为65°C（含2 mM Mg2+且不含DMSO）;（ii）除非另有说明，否则引物集可识别靶基因的所有已知转录本变体;（iii）只有一个基因被扩增。每个引物组都已通过qPCR和熔解曲线分析和凝胶电泳进行了验证。

ScienCell's GeneQuery™ Human Cytoskeletal Remodeling qPCR Array Kit (GQH-CYT) profiles 88 key genes involved in cytoskeletal remodeling with a particular focus on Rho GTPase actin cytoskeleton remodeling. The cytoskeleton is responsible for maintaining cell shape, scaffolding, and regulating intracellular transport. It is also involved in numerous signaling pathways, cellular division, vesicular trafficking, and motility. Microfilaments, which are primarily actin polymers, are part of the cytoskeleton and regulated by the Rho family of GTPases. Brief examples of how included genes may be categorized are shown below:

· Cytoskeletal components: ACTA1, ACTB, ACTG1, ACTN1, MYH10, MYL1

· Integrins: ITGA1, ITGA3, ITGAV, ITGB1, ITGB3

· Extracellular matrix components: COL1A1, COL2A1, COL4A1, LAMA1, LAMB1

· Rho signaling molecules: CAV1, CDC42, RAC1, RHOA, ROCK1, ROCK2

· Transcription factors: CDX1, CDX2, SP1, TCF7, TCF7L1

GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that recognizes and efficiently amplifies a specific target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+and no DMSO); (ii) the primer set recognizes all known transcript variants of the target gene, unless otherwise noted; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis and gel electrophoresis.

GeneQuery™ 人类细胞骨架重塑 qPCR 阵列板布局*（8 个粗体和斜体对照）

提示：基因选择可能会根据新的研究和开发进行更新

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