品名： 碧云天Hsp70 Rabbit Monoclonal Antibody

型号： AF1156 产品详情 金山科研平台现货促销

WB, Western blot; IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry; ICC, Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent Assay; ChIP, Chromatin Immunoprecipitation Assay.H, Human; M, Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr, Horse; Mk, Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, Zebrafish; All, all species expected.配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：

抗体详细信息如下:

About this Antibody
Name	Hsp70 Rabbit Monoclonal Antibody
Category	Rabbit Monoclonal Antibody (RabMAb); Primary antibody
Isotype	IgG
Purification	Affinity purification
About the Immunogen
Immunogen	Recombinant protein
Gene ID	3303/3304(Human); 15511/193740(Mouse); 108348108/24472/294254(Rat)
SwissProt	P0DMV9/P0DMV8(Human); P17879/Q61696(Mouse); P0DMW0/P0DMW1(Rat)
Synonyms	HSP70-1B; HSP70-2
Category	Cytoskeletal Signaling; Metabolism; Apoptosis
Background	The 70 kilodalton heat shock proteins (Hsp70s) are a family of conserved ubiquitously expressedheat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding, and help to protect cells from stress. When not interacting with a substrate peptide, Hsp70 is usually in an ATP bound state. Hsp70 by itself is characterized by a very weak ATPase activity, such that spontaneous hydrolysis will not occur for many minutes. As newly synthesized proteins emerge from the ribosomes, the substrate binding domain of Hsp70 recognizes sequences of hydrophobic amino acid residues, and interacts with them. This spontaneous interaction is reversible, and in the ATP bound state Hsp70 may relatively freely bind and release peptides. However, the presence of a peptide in the binding domain stimulates the ATPase activity of Hsp70, increasing its normally slow rate of ATP hydrolysis.

暂无