产品英文名称：Phc2 antibody (mAb)

产品中文名称：Phc2 抗体 (mAb)

Active Motif Phc2 抗体 (mAb)产品英文描述：

Background

Phc2, polyhomeotic homolog 2 (also known as EDR2, early development regulatory protein 2) is a component of the polycomb group (PcG) multiprotein PRC1 complex. The PRC1 complex is required to maintain the stable repression of the Hox genes during development. This chromatin-associated protein complex acts via chromatin remodeling and histone modifications. Phc2 has been shown to interact with PHC1, BMI1, MAPKAPK2 and MCRS1.

Immunogen

This Phc2 antibody was raised against a recombinant fragment of human Phc2.

Application Notes

This Phc2 antibody has been validated for use in the following applications:

ChIP: see reference 1

IF: see reference 2

IP: see reference 1

References

1. Isono, K. et. al. (2005) Mol. Cell. Bio. 25: 6694-6706.

2. Takada, Y. et. al. (2007) Development 134: 579-590.

Buffer

Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

Storage

Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Active Motif Phc2 抗体 (mAb)产品简介：