产品英文名称：CD4 (L3T4) MicroBeads, mouse

产品中文名称：美天旎美天旎小鼠CD4 (L3T4)微珠

Miltenyi 美天旎小鼠CD4 (L3T4) MicroBeads微珠产品研究背景：

CD4（L3T4）微珠，为 淋巴和非淋巴组织或外周血单细胞悬浮液中小鼠T辅助细胞的正选择或耗竭而开发的。该 CD4抗原表达在大多数胸腺细胞和成熟的T辅助细胞 ，对NK-T细胞的一个子集，并在上一个亚群水平较低

的树突状细胞。它表达于胸腺细胞的约90％， 脾细胞的25％和淋巴结细胞的55％。

美天旎小鼠CD4 (L3T4) MicroBeads微珠产品简介：

Components

2 mL CD4 (L3T4) MicroBeads, mouse:

MicroBeads conjugated to monoclonal anti-mouse CD4 antibodies (L3T4; isotype: ratIgG2b;).

Size

For 2×10*9 total cells, up to 200 separations.

Product format

CD4 (L3T4) MicroBeads are supplied as a suspension containing stabilizer and 0.05% sodium azide.

Storage

Store protected from light at 4～8 °C. Do not freeze.The expiration date is indicated on the vial label.

Miltenyi 美天旎小鼠CD4 (L3T4) MicroBeads微珠产品应用：

●Isolation of mouse CD4+ T cells from spleen and lymph nodes,brain tissue or bronchoalveolar lavage to study cytokine

●Isolation of CD4-CD8+thymocytes by depleting CD4+cells.

●Isolation of CD4+ T cells for adoptive cell transfer experimentsto study IgE synthesis,the infectious mechanism of mammary tumor viruses or mouse models for diseases such as diabetes,

hepatitis,arthritis or leishmaniasis.secretion and surface marker expression.

美天旎小鼠CD4 (L3T4) MicroBeads微珠产品英文描述：

Mouse CD4 (L3T4) MicroBeads were developed for positive selection or depletion of mouse T helper cells from single-cell suspensions of lymphoid and non-lymphoid tissues or from peripheral blood.

The CD4 antigen is expressed on most thymocytes and mature T helper cells, and at lower levels on a subpopulation of dendritic cells. CD4 acts as an accessory molecule in the recognition of MHC class II/peptide complexes by the TCR heterodimer on CD4⁺ T helper cells. The CD4 antigen is expressed on approximately 90% of thymocytes, 25% of splenocytes, and 55% of lymph node cells.