金山科研平台，产品价格货期咨询微信：jinshanbio Assay Type:Solid Phase Sandwich ELISA Format:96-well strip plate Assay Length:4.5 hours Sample Type & Volume Required Per Well:Cell Culture Supernates (50 µL), Cell Lysates (10 µL), Serum (10 µL), EDTA Plasma (10 µL), Heparin Plasma (10 µL) Sensitivity:21.9 pg/mL Assay Range:62.5 - 4,000 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, Cell Lysates, EDTA Plasma) Specificity:Natural and recombinant mouse PCSK9. This kit detects 60 kDa, 53 kDa, and LDLR-complexed recombinant mouse PCSK9. Cross-reactivity: Interference:No significant interference observed with available related molecules. Molecule Information: Proprotein Convertase 9/PCSK9 Aliases: FH3; HCHOLA3; NARC-1; PC9; PCSK9 Entrez Gene IDs: 255738 (Human); 100102 (Mouse); 298296 (Rat) Background: Proprotein Convertases This family of serine proteases consists of furin and proprotein convertases encoded by PCSK genes. They are important in a variety of processes. Furin has an essential role in embryogenesis and homeostasis and is implicated in various pathologies such as cancer, neurodegenerative diseases and anthrax. Mutations in the PC1/PCSK1 gene are associated with obesity and impaired prohormone processing.