金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: MyBPC3 Long Name: Myosin Binding Protein C, Cardiac Aliases: CMH4; C-protein, cardiac muscle isoform; FHC; MYBP-C Entrez Gene IDs: 4607 (Human); 17868 (Mouse) Background: MyBPC3 Cardiac myosin binding protein C3 (MyBPC3) is a 140 kDa thick filament-associated protein located in the crossbridge region of cardiac muscle sarcomeres. It is composed of eight Ig-like domains and three fibronectin 3-like domains and is known to be a physiological substrate of cAMP-dependent protein kinase. MyBPC3 has a role in sarcomeric structure and in the regulation of cardiac muscle contraction. MyBPC3 is released into the coronary effluent during myocardial infarction. Mutations in MyBPC3 are associated with hypertrophic cardiomyopathy.