R&D Systems代理MAB7020 Human DEK MAb (Clone 715524) (100 UG)-试剂-金山科研平台

R&D Systems代理MAB7020 Human DEK MAb (Clone 715524) (100 UG)

2025-06-28

货号：MAB7020

品牌：R&D Systems

规格：100ug

目录价：￥3720.00

市场价格：￥2976.00

会员价格：￥2976.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: DEK Entrez Gene IDs: 7913 (Human); 110052 (Mouse); 306817 (Rat) Background: DEK

View DEK IHC images. The DEK oncogene is an approximately 45 kDa phosphoprotein with pleiotropic activities. It is a chromatin remodeling factor, a transcriptional coactivator and corepressor, a component of RNA spliceosomes, and a promoter of DNA repair during apoptosis. DEK is upregulated in many cancers and promotes epithelial cell transformation. It functions as a proinflammatory factor when secreted by activated macrophages. It is an autoantigen in juvenile arthritis and lupus and a target of chromosomal translocation with the CAN gene in acute myelogenous leukemia. DEK contains one SAP domain (aa 149-183), one nuclear localization sequence (aa 205-221), and a DNA-binding C-terminal domain (aa 321-375).

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