R&D Systems代理MAB6976 Human/Mouse/Rat STIM1 MAb (Clone 705111) (100 UG)-试剂-金山科研平台

R&D Systems代理MAB6976 Human/Mouse/Rat STIM1 MAb (Clone 705111) (100 UG)

2025-06-27

货号：MAB6976

品牌：R&D Systems

规格：100ug

目录价：￥3720.00

市场价格：￥2976.00

会员价格：￥2976.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: STIM1 Long Name: Stromal Interaction Molecule 1 Aliases: GOK Entrez Gene IDs: 6786 (Human); 20866 (Mouse); 361618 (Rat) Background: STIM1

View STIM1 IHC images. STIM-1 (stromal interaction molecule 1), previously called GOK, is a 90 kDa type I transmembrane protein of the endoplasmic reticulum (ER). When STIM-1 senses depletion of calcium in the ER via its EF-hand domain, it interacts with the plasma membrane Ca2+ release-activated Ca2+ (CRAC) channel Orai1, increasing Ca2+ influx. Defects in STIM1 are the cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 2 (IDTICED2).

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