R&D Systems代理MAB6925 Human Tensin 4/CTEN MAb (Clone 684524) (100 UG)-试剂-金山科研平台

R&D Systems代理MAB6925 Human Tensin 4/CTEN MAb (Clone 684524) (100 UG)

2025-06-28

货号：MAB6925

品牌：R&D Systems

规格：100ug

目录价：￥3720.00

市场价格：￥2976.00

会员价格：￥2976.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Tensin 4/CTEN Aliases: CTEN; TNS4 Entrez Gene IDs: 84951 (Human); 217169 (Mouse); 303517 (Rat) Background: Tensin 4

View Tensin 4/CTEN IHC images. Tensin 4, also known as CTEN, is a 90 kDa cytoplasmic protein that is associated with focal adhesions in epithelial cells and is upregulated in several carcinomas. It promotes tumorigenesis by disrupting the attachment of focal adhesions to the cytoskeleton, promoting epithelial-mesenchymal transition, and binding nuclear beta-Catenin. Tensin 4 is cleaved by Caspase-3 at Asp570-Ser571 during apoptosis. It contains a serine-rich region (aa 168-324), one SH2 domain (aa 449-556), and a phosphatase domain (aa 548-714).

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