R&D Systems代理MAB6908 Human APH1A MAb (Clone 665404) (100 UG)-试剂-金山科研平台

R&D Systems代理MAB6908 Human APH1A MAb (Clone 665404) (100 UG)

2025-06-28

货号：MAB6908

品牌：R&D Systems

规格：100ug

目录价：￥3720.00

市场价格：￥2976.00

会员价格：￥2976.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: APH1A Long Name: gamma-Secretase Subunit Anterior Pharynx Defective 1 Homolog A Entrez Gene IDs: 51107 (Human); 100039623 (Mouse) Background: APH1A

View APH1A IHC images. Anterior pharynx-defective 1 (APH1A) is a widely expressed 36 kDa 7-transmembrane protein found in the endoplasmic reticulum and Golgi. APH1A is a component of the gamma secretase proteolytic complex which cleaves multiple substrates within their transmembrane domains. This activity liberates the intracellular domains of ErbB4, Neuregulin-1, and Notch receptors in addition to the A-beta peptide from the amyloid precursor protein (APP). Alternate splicing generates a short isoform of human APH1a that lacks 18 amino acids at the C-terminus.

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