金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: TORC3 Long Name: Transducer of Regulated CREB-binding Protein 3 Aliases: CRTC3 Entrez Gene IDs: 64784 (Human); 70461 (Mouse); 365297 (Rat) Background: TORC3 TORC3, also known as CREB-regulated transcription coactivator 3 (CRTC3), is a 67 kDa protein that functions as a coactivator for CREB1 in promoting transcription through both consensus and variant cAMP response element (CRE) sites. TORC3 activity is important in regulating the expression of genes involved in cellular energy metabolism. Its binding to the HTLV-1 protein Tax enhances HTLV-1 transcription, whereas its binding to cellular Bcl3 inhibits HTLV-1 transcription. Alternate splicing of mouse TORC3 generates isoforms that lack the N-terminal 299 amino acids.