货号:AG372
品牌:Merck Millipore
规格:EA
目录价:¥2390.00
市场价格:¥2031.50
会员价格:¥1912.00
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Description:
Glutamate Transporter, control peptide for MAB1587
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Trade Name:
Chemicon (Millipore)
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Qty/Pk:
100 µg
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Product Overview:
Glutamate Transporter (EAAC1) control peptide.
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Key Applications:
Cell Function Assay
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Application Notes:
Antibody blocking (MAB1587) Optimal working concentration must be determined by the end user.
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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UniProt Summary:
FUNCTION: SwissProt: P43005 # Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5 (By similarity).SIZE: 524 amino acids; 57100 Da SUBUNIT: Interacts with ARL6IP5/PRAF3 (By similarity).SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Expressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral cortical layers).PTM: Glycosylated.DISEASE: SwissProt: P43005 # Defects in SLC1A1 may be a cause of dicarboxylicamino aciduria [MIM:222730]; also known as glutamate-aspartate transport defect. This is as defect in renal and probably intestinal transport of glutamic and aspartic acids and is associated with moderate hyperprolinemia.SIMILARITY: SwissProt: P43005 ## Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family.
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Species:
Rat
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Brand Family:
Chemicon
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Presentation:
BSA-EDAC conjugated peptide. Liquid.
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Storage Conditions:
Store at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Gene Symbol:
-
SLC1A1
-
EAAC1
-
EAAT3
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Product Name:
Glutamate Transporter, control peptide for MAB1587
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Alternate Names:
EAAC1
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Concentration:
1 mg/mL
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UniProt Number:
P43005
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Entrez Gene Number:
NM_004170.4
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