货号：AG221

品牌：Merck Millipore

规格：100Ug

目录价：￥3841.00

市场价格：￥3264.85

会员价格：￥3072.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Dopamine D2 Receptor, control peptide for AB5084P View All» Trade Name: Chemicon (Millipore) View All» Qty/Pk: 100 µg View All» Product Overview: 28 amino acid peptide sequence from the human D2 R within the cytoplasmic loop #3. The 28 amino acid sequence is shared by both the long and short form. View All» Key Applications: Cell Function Assay View All» Application Notes: For use in blocking the staining of AB5084P. Optimal working dilution must be determined by the end user. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. View All» UniProt Summary: FUNCTION: SwissProt: P14416 # This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.SIZE: 443 amino acids; 50619 Da SUBUNIT: Interacts with GPRASP1, neurabin-2 and CLIC6 (By similarity). Interacts with CADPS and CADPS2.SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.DISEASE: SwissProt: P14416 # It has been suggested that DRD2 is involved in psychiatric disorders; especially in schizophrenia. & Defects in DRD2 are associated with myoclonus dystonia (MD) [MIM:159900]; also known as myoclonic dystonia, alcohol- responsive dystonia and dystonia-11 (DYT11). MD is a movement disorder characterized by involuntary lightning jerks and dystonic movements and postures alleviated by alcohol. Inheritance is autosomal dominant. The age of onset, pattern of body involvement, presence of myoclonus and response to alcohol are all variable.SIMILARITY: SwissProt: P14416 ## Belongs to the G-protein coupled receptor 1 family. View All» Species: Human View All» Brand Family: Chemicon View All» Presentation: Liquid in PBS, pH 7.5 containing 0.05% sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Gene Symbol:

• DRD2

• D

• D2R

• D2DR
  View All» Product Name: Dopamine D2 Receptor, control peptide for AB5084P View All» Concentration: 1 mg/mL View All» UniProt Number: P14416 View All» Entrez Gene Number:
  • NM_000795.2

  • NM_016574.2
    View All»
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