货号：ABT303

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PITRM1 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~117 kDa observed. An uncharacterized band may appear at ~30 kDa in some lysates. View All» Immunogen: GST-tagged recombinant protein corresponding to human PITRM1. View All» Background Information: PITRM1 (Presequence protease, mitochondrial) is an ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. It is specific for peptides in the range of 10 to 65 residues and able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer's disease. PITRM1 shows a preference for cleavage after small polar residues and before basic residues, but without any positional reference. View All» Species Reactivity:

• Human

• Mouse
  View All» Species Reactivity Note: Demonstrated to react with Human and Mouse. View All» Control: Human placenta tissue lysate View All» Quality Assurance: Evaluated by Western Blotting in human placenta tissue lysate.Western Blotting Analysis: A 1:300 dilution of this antibody detected PITRM1 in 30 µg of human placenta tissue lysate. View All» Purification Method: Antigen Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing PBS with 0.1% sodium azide and 50% glycerol. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. View All» UniProt Number: Q5JRX3 View All» Gene Symbol:
  • PITRM1

  • MP1
    View All» Alternate Names:
    • Presequence protease, mitochondrial

    • hPreP

    • Pitrilysin metalloproteinase 1

    • Metalloprotease 1

    • hMP1

    • PITRM1
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Product Name: Anti-PITRM1 View All» Concentration: 0.14 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 150 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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