金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: MGMT Long Name: O-6 Methylguanine-DNA Methyltransferase Entrez Gene IDs: 4255 (Human); 17314 (Mouse) Background: MGMT The O-6-methylguanine-DNA-methyl transferase (MGMT) is involved in the direct repair of DNA alkylated at the O⁶ position of guanine. MGMT transfers the alkyl group to its own cysteine thereby inactivating the MGMT molecule. Therefore, the number of MGMT molecules correlates directly with the cell's ability to withstand DNA alkylation.