货号：ABT108

品牌：Merck Millipore

规格：100Ug

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Lnk/SH2B adapter protein 3 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes Lnk/SH2B adapter protein 3 at the C-terminus. View All» Molecular Weight: ~80 kDa observed. The calculated molecular weight is 63 kDa, however Lnk/SH2B adapter protein 3 has been shown as a ~80 kDa band in western blots (Li, Y., et al. (2000). J Immunol. 164:5199-5206.) View All» Epitope: C-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of human Lnk/SH2B adapter protein 3. View All» Background Information: Lnk is an SH2B3 multidomain adaptor protein that is primarily expressed in lymphocytes. It contains the characteristic pleckstrin homology (PH); src homology 2 (SH2); dimerization; and proline-rich domains. Lnk functions as a negative regulator of B cell proliferative processes via interaction with Jak2 and Mpl proteins, and inhibition of the PI3/Akt/STAT5 signaling pathway. Previous studies have implicated Lnk in celiac disease type 13. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. Other homologies: Rat (78% sequence homology) and Mouse (72% sequence homology). View All» Control: HepG2 cell lysate View All» Quality Assurance: Evaluated by Western Blot in HepG2 cell lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected Lnk/SH2B adapter protein 3 on 10 µg of HepG2 cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9UQQ2 View All» Entrez Gene Number: NP_005466 View All» Gene Symbol:

• SH2B3

• LNK
  View All» Alternate Names:
  • SH2B adapter protein 3

  • Lymphocyte adapter protein

  • Lymphocyte-specific adapter protein Lnk

  • Signal transduction protein Lnk
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Product Name: Anti-Lnk/SH2B adapter protein 3 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：https://16ao.com/thread-159627.htm
    © Merck Millipore代理ABT108 Anti-Lnk/SH2B adapter protein 3 Antibody;store at +2℃ to +8℃，产品报价联系微信jinshanbio