货号：ABS88

品牌：Merck Millipore

规格：100UL

目录价：￥4285.00

市场价格：￥3642.25

会员价格：￥3428.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-phospho-mTOR (Thr2164) Antibody | ABS88 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes mTOR phosphorylated at Thr2164. View All» Molecular Weight: 289 kDa calculated View All» Epitope: Phosphorylated Thr2164 View All» Immunogen: KLH-conjugated linear peptide corresponding to human mTOR phosphorylated at Thr2164. View All» Background Information: The mammalian target of rapamycin (mTOR), also known as FRAP, RAFT, or RAPT, is a ubiquitously expressed serine/threonine kinase that belongs to the phosphoinositide 3-kinase–related kinase (PIKK) family. mTOR functions as a downstream effector in the PI3K pathway and is activated by the Akt kinase. mTOR responds to signals from growth factors and promotes protein synthesis underlying cell proliferation, by activation of the S6 kinase and inhibition of the 4E-BP protein involved in protein translation. Several studies have suggested that the proliferative functions of mTOR may contribute to the development of cancer. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Western Blot Analysis: A representative lot was used by an independent laboratory in HEK293 cell lysate. (Ekim, B., et al. (2011). MCB. [Epub ahead of print].) View All» Control: Unmodified and phosphorylated mTOR peptides View All» Quality Assurance: Dot Blot Specificity Analysis: Unmodified and phosphorylated mTOR peptides were probed with Anti-phospho-mTOR (Thr2164) (1:1,000 dilution). View All» Purification Method: Unpurified View All» Presentation: Rabbit polyclonal serum containing 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: P42345 View All» Entrez Gene Number: NP_004949 View All» Gene Symbol:

• MTOR

• FRAP

• FRAP1

• FRAP2

• RAFT1

• RAPT1
  View All» Alternate Names:
  • Serine/threonine-protein kinase mTOR

  • FK506-binding protein 12-rapamycin complex-associated protein 1

  • FKBP12-rapamycin complex-associated protein

  • Mammalian target of rapamycin

  • mTOR

  • Mechanistic target of rapamycin

  • Rapamycin and FKBP12 target 1

  • Rapamycin target protein 1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Dot Blot

    • Western Blotting
      View All» Product Name: Anti-phospho-mTOR (Thr2164) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»
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