货号：ABS68

品牌：Merck Millipore

规格：

目录价：￥4264.00

市场价格：￥3624.40

会员价格：￥3411.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Fer Antibody | ABS68 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~90 kDa observed. Uncharacterized bands may be visible at ~38 and ~58 kDa in some lysates. View All» Epitope: 0 View All» Immunogen: KLH-conjugated linear peptide corresponding to human Fer. View All» Background Information: FER tyrosine kinase is involved in cadherin, PECAM-1, and integrin mediated cytoskeletal connections. More recent research has also linked FER to decreasing the innate immune response. FER has also been implicated in the control of lipopolysaccharide induced epithelial dysfunction. FER has been shown to be essential in microtubule characteristics in the oocyte meiotic spindle and could also play a role in germinal vesicle breakdown. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with Human, Mouse and Rat. View All» Application Notes: Immunohistochemistry Analysis: 1:500 dilution of a representative lot of this antibody detected Fer in lymphoid cells within the germinal centers and outside the mantle zone of normal human tonsil tissue. View All» Control: HEK293 cell lysate View All» Quality Assurance: Evaluated by Western Blot in HEK293 cell lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected Fer on 10 µg of HEK293 cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P16591 View All» Entrez Gene Number: NP_005237 View All» Gene Symbol:
  • FER

  • TYK3
    View All» Alternate Names:
    • Tyrosine-protein kinase Fer

    • Proto-oncogene c-Fer

    • Tyrosine kinase 3

    • p94-Fer
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» Entrez Gene Summary: Summary: Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Tyrosine kinase of the non-receptor type. Probably performs an important function, perhaps in regulatory processes such as cell cycle control.CATALYTIC ACTIVITY: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note: Associated with the chromatin.TISSUE SPECIFICITY: Expressed in a variety of lymphoid cell lines.SEQUENCE SIMILARITIES: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. Contains 1 FCH domain. Contains 1 protein kinase domain. Contains 1 SH2 domain. View All» Product Name: Anti-Fer View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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