货号：ABS41

品牌：Merck Millipore

规格：EA

目录价：￥3108.00

市场价格：￥2641.80

会员价格：￥2486.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Plekhm3 Antibody | ABS41 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes Plekhm3 at the C-terminus. View All» Molecular Weight: ~ 75 kDa observed (Takahasi, M. University Health Network Toronto). An uncharacterized band appears at ~ 50 kDa. View All» Epitope: C-terminus View All» Immunogen: Linear peptide corresponding to mouse Plekhm3 at the C-terminus. View All» Isotype: IgG View All» Background Information: Plekhm3 (Pleckstrin homology domain-containing family M member 3) is also known as DAPR (differentiation associated protein). Plekhm3 interacts with phosphatidylinositol 3-kinase signaling pathway component protein kinase B (PKB). It is also involved in the PI3K signaling pathway by working as a scaffold protein during skeletal muscle differentiation. Plekhm3 is primarily found in the cytosol but will move with PKB to the membrane once differentiation begins. View All» Species Reactivity:

• Mouse

• Human

• Rat
  View All» Species Reactivity Note: Demonstrated to react with mouse. Predicted to react with human and rat based on 100% sequence homology. View All» Control: RAW264.7 cell lysate View All» Quality Assurance: Evaluated by Western Blot in RAW264.7 cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected Plekhm3 on 10 µg of RAW264.7 cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide and 50% glycerol. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. View All» UniProt Number: Q8BM47 View All» Entrez Gene Number: NP_001034582 View All» Gene Symbol:
  • DAPR

  • PLEKHM3

  • PLEKHM1L

  • Plekhm3
    View All» Alternate Names:
    • pleckstrin homology domain containing, family M, member 3

    • pleckstrin homology domain containing, family M, member 1-like

    • differentiation associated protein

    • pleckstrin homology domain-containing family M member 3

    • PH domain-containing family M member 3
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: SEQUENCE SIMILARITIES: Contains 2 PH domains.Contains 1 phorbol-ester/DAG-type zinc finger. View All» Product Name: Anti-Plekhm3 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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