货号:ABS228
品牌:Merck Millipore
规格:
目录价:¥3206.00
市场价格:¥2725.10
会员价格:¥2564.80
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Description:
Anti-Glucose-6-Phosphate Dehydrogenase Antibody | ABS228
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Molecular Weight:
~55 kDa observed. Uniprot describes 3 isoforms produced by alternative splicing at ~59 kDa, ~62 kDa, and ~64 kDa.
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Immunogen:
KLH-conjugated linear peptide corresponding to human Glucose-6-Phosphate Dehydrogenase.
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Background Information:
Glucose-6-Phosphate Dehydrogenase (G6PD) is the rate-limiting enzyme in the pentose phosphate pathway that catalyzes the oxidation of catalyzes the oxidation of glucose-6-phosphate (G6P) to form pentose sugars for subequent biosynthetic pathways. Glucose-6-Phosphate Dehydrogenase also produces nicotinamide adenine dinucleotide phosphate (NADPH), an important electron donor that plays a protective role against oxidative stress, especially in red blood cells. Deficiencies in glucose-6-phosphate dehydrogenase may disrupt cell growth, cell signaling, and embryonic development. It is also fairly well established that mutations in the glucose-6-phosphate dehydrogenase result in a highly varied condition known as chronic non-spherocytic hemolytic anemia.
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Species Reactivity:
Human
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Species Reactivity Note:
Demonstrated to react with Human. Predicted to react with Baboon and Rhesus Macaque based on 100% sequence homology. Other homologies: Rabbit, Rat, Sheep, Bovine, and Frog (93% sequence homology) and Mouse (86% sequence homology)..
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Control:
MCF7 cell lysate
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Quality Assurance:
Evaluated by Western Blot in MCF7 cell lysate.Western Blot Analysis: 0.1 µg/mL of this antibody detected Glucose-6-Phosphate Dehydrogenase in 10 µg of MCF7 cell lysate.
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Purification Method:
Unpurified
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Presentation:
Rabbit polyclonal serum containing 0.05% sodium azide.
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Storage Conditions:
Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
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UniProt Number:
P11413
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Entrez Gene Number:
NP_000393
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Gene Symbol:
G6PD
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Alternate Names:
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Glucose-6-phosphate 1-dehydrogenase
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G6PD
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Glucose-6-Phosphate Dehydrogenase
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
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Product Name:
Anti-Glucose-6-Phosphate Dehydrogenase
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Antibody Type:
Polyclonal Antibody
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Qty/Pk:
100 µL
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Format:
Serum
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Host:
Rabbit
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