货号:ABS224
品牌:Merck Millipore
规格:100UL
目录价:¥4438.00
市场价格:¥3772.30
会员价格:¥3550.40
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Description:
Anti-YVH1 Antibody | ABS224
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Molecular Weight:
~38 kDa observed. An uncharacterized band at ~36 kDa may be observed in some cell lysates.
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Epitope:
0
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Immunogen:
GST-tagged recombinant protein corresponding to human YVH1.
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Background Information:
Yeast VH1-related phosphatase (YVH1), also known as “dual specificity protein phosphatase 12” (DUSP12) is a ubiquitous phosphatase, with relatively high levels of expression in the ovary, testis, spleen, and peripheral blood leukocytes. YVH1 primarily removes phosphate groups from phosphorylated serine, threonine, and tyrosine residues in its target substrates. However, YVH1 also contains a zinc-binding domain which may enable it to interact with other proteins involved in cell growth, cell survival, and cell cycle progression. YVH1 may also be involved in the assembly of ribosomes, and in the biogenesis of the 60S ribosomal subunit. It can be targeted to different subcellular locations by phosphorylation of its Ser335 residue located in the zinc-binding domain.
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Species Reactivity:
Human
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Species Reactivity Note:
Demonstrated to react with Human.
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Application Notes:
Western Blot Analysis: A representative lot detected YVH1 in 10 µg of Jurkat cell lysate.
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Control:
HeLa cells
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Quality Assurance:
Evaluated by Western Blot in HeLa cells.Western Blot Analysis: A 1:500 dilution of this antibody detected YVH1 in 10 µg of HeLa cell lysate.
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Purification Method:
Affinity purified
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Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
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Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
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UniProt Number:
Q9UNI6
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Entrez Gene Number:
NP_009171
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Gene Symbol:
DUSP12
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Alternate Names:
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Dual specificity protein phosphatase 12
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Dual specificity tyrosine phosphatase YVH1
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
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Product Name:
Anti-YVH1
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Antibody Type:
Polyclonal Antibody
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Qty/Pk:
100 µL
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Format:
Affinity Purified
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Host:
Rabbit
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