货号：ABS218

品牌：Merck Millipore

规格：100Ug

目录价：￥4285.00

市场价格：￥3642.25

会员价格：￥3428.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-phospho-DBC1 (Thr454) Antibody | ABS218 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes DBC1 phosphorylated at Thr454. View All» Molecular Weight: ~130 kDa observed. Uniprot states the calculated molecular weight is 103 kDa but has been shown at ~130kDa (Satoh, M., et al. (1995). Brain Res Dev Brain Res. 87(2):111-119). View All» Epitope: Phosphorylated Thr454 View All» Immunogen: KLH-conjugated linear peptide corresponding to human DBC-1 phosphorylated at Thr454. View All» Background Information: Deleted in breast cancer gene 1 protein (DBC1) is a large, nuclear protein with multiple functions in cell survival that binds directly to the estrogen receptor α (ERα) hormone-binding domain in a strict ligand-independent manner. DBC1 promotes p53-mediated apoptosis by binding to and inhibiting the deacetylase activity of SirT1, resulting in increased p53 acetylation levels and activity. It is ubiquitously expressed in 84 to 100% of neoplastic breast, lung, and colon tissues. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Peptide Inhibition Assay: A 1:500 dilution from a representative lot blocked DBC-1 phosphorylated at Thr454 in untreated and etoposide treated Jurkat cell lysates. View All» Control: Untreated and etoposide treated Jurkat cell lysates View All» Quality Assurance: Evaluated by Western Blot in untreated and etoposide treated Jurkat cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected DBC-1 phosphorylated at Thr454 in 10 µg of etoposide treated Jurkat cell lysates. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8N163 View All» Entrez Gene Number: NP_066997 View All» Gene Symbol:

• KIAA1967

• DBC1
  View All» Alternate Names:
  • DBIRD complex subunit KIAA1967

  • Deleted in breast cancer gene 1 protein

  • DBC-1

  • DBC.1

  • p30 DBC
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Peptide Inhibition Assay
      View All» Product Name: Anti-phospho-DBC1 (Thr454) View All» Concentration: 0.5 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://16ao.com/thread-159498.htm
      © Merck Millipore代理ABS218 Anti-phospho-DBC1 (Thr454) Antibody;store at +2℃ to +8℃，产品报价联系微信jinshanbio