货号：ABS19

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-UFM1-activating enzyme Antibody | ABS19 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~50 kDa observed. An uncharacterized band may appear at ~22 kDa and ~180 kDa in some lysates. View All» Immunogen: KLH-conjugated linear peptide corresponding to human UFM1-activating enzyme. View All» Background Information: Ubiquitin-fold modifier 1 (UFM1)-activating enzyme, also referred to as Uba5, is a ubiquitin-like post-translational modifier associated with the mitochondria. UFM1-activating enzyme is essential in erythroid development and differentiation and is also important in regulation of haematopoiesis. UFM1-activating enzyme could be a potential target for therapies to control Leishmaniasis. View All» Species Reactivity:

• Human

• Mouse

• Ox
  View All» Species Reactivity Note: Demonstrated to react with human and mouse. Predicted to react with ox based on 100% sequence homology. Other homologies: rat (92% sequence homology). View All» Control: Human colon tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human colon tissue lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected UFM1-activating enzyme on 10 µg of human colon tissue lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9GZZ9 View All» Entrez Gene Number: NP_079094. View All» Gene Symbol:
  • UBA5

  • UBE1DC1
    View All» Alternate Names:
    • Ubiquitin-like modifier-activating enzyme 5

    • Ubiquitin-activating enzyme 5

    • ThiFP1

    • UFM1-activating enzyme

    • Ubiquitin-activating enzyme E1 domain-containing protein 1
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. A pseudogene located on chromosome 1 has also been identified. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: E1-like enzyme which activates UFM1 and SUMO2. SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note: Localizes mainly in cytoplasm, while it mainly localizes to the nucleus in presence of SUMO2. TISSUE SPECIFICITY: Widely expressed. SEQUENCE SIMILARITIES: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. View All» Product Name: Anti-UFM1-activating enzyme View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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