货号：ABN16

品牌：Merck Millipore

规格：

目录价：￥4502.00

市场价格：￥3826.70

会员价格：￥3601.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GPR56 Antibody | ABN16 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes GPR56 at the N-terminus. View All» Molecular Weight: 77 kDa calculated View All» Epitope: N-terminus View All» Immunogen: Linear peptide corresponding to the N-terminus sequence of mouse GPR56. View All» Isotype: IgG View All» Background Information: G-protein coupled receptor 56 (GPR56) is a novel, multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and containing a characteristic, extracellular GPS domain. Although newly discovered, studies have suggested roles for the protein in the adhesion between developing neurons, regulating the integrity of pial basement membranes, regulating corticogenesis, and may also be involved in cancer cell metastasis and adhesion. Expression has been observed in a wide variety of peripheral tissues, but the most significant levels have been reported in brain, heart, and thyroid gland. Defects in GPR56 expression cause bilateral frontoparietal polymicrogyria (BFPP), a malformation of the brain in humans that is characterized by ataxia, seizures, disfigurement of the cerebral cortex, and mental retardation. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with mouse. View All» Application Notes: Immunohistochemistry Analysis: 1:200 dilution of this antibody from a previous lot detected GPR56 in anal carcinoma and testicular teratoma tissue. View All» Control: Inflammatory skin biopsy tissue View All» Quality Assurance: Evaluated by Immunohistochemistry in inflammatory skin biopsy tissue.Immunohistochemistry Analysis: 1:200 dilution of this antibody detected GPR56 in inflammatory skin biopsy tissue. View All» Purification Method: Affinity Purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.05% sodium azide with 50% Glycerol. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. View All» UniProt Number: Q8K209 View All» Entrez Gene Number: NP_061370 View All» Gene Symbol:

• GPR56

• TM7XN1

• TM7LN4

• EGF-TM7-like

• BFPP
  View All» Alternate Names:
  • G protein-coupled receptor 56

  • 7-transmembrane protein with no EGF-like N-terminal domains-1

  • Protein TM7XN1

  • G-protein coupled receptor 56
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry View All» UniProt Summary: FUNCTION: Could be involved in cell-cell interactions.SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. SEQUENCE SIMILARITIES: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.Contains 1 GPS domain. View All» Product Name: Anti-GPR56 View All» Concentration: 0.45 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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