货号：ABE59

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-ELK4 Antibody | ABE59 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~ 44/48 kDa observed View All» Immunogen: KLH-conjugated linear peptide corresponding to human ELK4. View All» Isotype: IgG View All» Background Information: ETS domain-containing protein Elk-4 (ELK4), also known as Sap-1, belongs to the ETS family. This nuclear transcription factor contains a single ETS DNA-binding domain. Elk-4 is known to function in cooperation with serum response factor (SRF), forming a ternary complex that is a required component of Ras-ERK signal transduction pathways. Studies have shown ELK4 to be targeted by p38 MAPK, ERK, and JNK families. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with mouse. Predicted to react with human based on 100% sequence homology. View All» Control: Mouse brain tissue lysate View All» Quality Assurance: Evaluated by Western Blot in mouse brain tissue lysate.Western Blot Analysis: 1:1,000 dilution of this antibody detected SIX1 on 10 µg of mouse brain tissue lysate. View All» Purification Method: Unpurified View All» Presentation: Rabbit polyclonal serum containing 0.5% sodium azide. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: P28324 View All» Entrez Gene Number: NP_068567 View All» Gene Symbol:

• ELK4

• SAP-1

• SAP1
  View All» Alternate Names:
  • ELK4, ETS-domain protein (SRF accessory protein 1)

  • ETS domain-containing protein Elk-4

  • Serum response factor accessory protein 1

  • ETS-domain protein

  • SRF accessory protein 1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Forms a ternary complex with the serum response factor (SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously.SUBCELLULAR LOCATION: Nucleus. SEQUENCE SIMILARITIES: Belongs to the ETS family.Contains 1 ETS DNA-binding domain. View All» Product Name: Anti-ELK4 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»
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