Merck Millipore代理ABE325 Anti-monomethyl Histone H2B (Lys5)

2025-06-28

货号:ABE325

品牌:Merck Millipore

规格:

目录价:¥4934.00

市场价格:¥4193.90

会员价格:¥3947.20

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-monomethyl-Histone H2B (Lys5) Antibody | ABE325 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the N-terminus of Histone H2B monomethylated at Lys5. View All» Molecular Weight: ~16 kDa observed View All» Epitope: N-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to the N-terminus of human Histone H2B monomethylated at Lys5. View All» Background Information: Histone H2B is one of four histones that form a core octameric structure required for the packaging of DNA into nucleosomes, the most basic level of chromatin arrangement. Histones undergo a number of post-translational modifications (PTM) at their N- and C-terminal tails, which can influence chromatin structure and stability; and consequently, transcription, and DNA replication and repair. Histone methylation is involved in many key epigenetic phenomena, including maintaining the boundaries between heterochromatin and euchromatin. Histone methylation of lysines is generally associated with transcriptional repression; however, some modifications, such as methylation of Lys4 of histone H3, are associated with transcriptional activation. The role of methylation of Lys5 of Histone 2B is unknown. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human, Mouse, and Rat. View All» Application Notes: Dot Blot Analysis: Unmodified and various modified Histone peptides (see table) were probed with Anti-monomethyl-Histone H2B (Lys5) (5 µg/mL).Immunoprecipitation Analysis: A representative lot immunoprecipitated monomethyl-Histone H2B (Lys5) from HeLa cell lysate. View All» Control: Hela cell acid extract View All» Quality Assurance: Evaluated by Western Blot in HeLa acid extract and recombinant Histone proteins.Western Blot Analysis: A 1 µg/mL of this antibody detected monomethyl Histone H2B (Lys5) in 10 µg of HeLa acid extract. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P62807 View All» Entrez Gene Number: NP_003509 View All» Gene Symbol:

  • HIST1H2BC

  • H2BFL

  • HIST1H2BE

  • H2BFH

  • HIST1H2BF

  • H2BFG

  • HIST1H2BG

  • H2BFA

  • HIST1H2BI

  • H2BFK

    View All» Alternate Names:
    • Histone H2B type 1-C/E/F/G/I

    • Histone H2B.1 A

    • Histone H2B.a

    • H2B/a

    • Histone H2B.g

    • H2B/g

    • Histone H2B.h

    • H2B/h

    • Histone H2B.k

    • H2B/k

    • Histone H2B.l

    • H2B/l

      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Flow Cytometry

        View All» Product Name: Anti-monomethyl-Histone H2B (Lys5) View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Mouse View All»

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