货号：ABE302

品牌：Merck Millipore

规格：100Ug

目录价：￥4899.00

市场价格：￥4164.15

会员价格：￥3919.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-ATDC Antibody | ABE302 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~66 kDa observed View All» Immunogen: KLH-conjugated linear peptide corresponding to a region within amino acides 565 to 595 of human ATDC . View All» Background Information: Ataxia telangiectasia group D-complementing (ATDC) protein, also known as tripartite motif containing protein 29 (TRIM29), belongs to the TRIM protein family. Studies have shown that ATDC may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. The ATDC gene is located at 11q23 where loss of heterozygosity has been observed in many kinds of cancers; underexpression of ATDC has been reported in breast and prostate cancer. ATDC may also complement the radiosensitivity defect of ataxia telangiectasia phenotype. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with Human, Mouse, and Rat. View All» Application Notes: Immunoprecipitation Analysis: A representative lot was used by an independent laboratory in IP. (Yuan, Z., et al. (2010). J Biol Chem. 285(50):39329-39338.) View All» Control: RAW 264.7 cell lysate View All» Quality Assurance: Evaluated by Western Blot in RAW 264.7 cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected ATDC on 10 µg of RAW 264.7 cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q14134 View All» Entrez Gene Number: NP_036233 View All» Gene Symbol: TRIM29, ATDC View All» Alternate Names:
  • Ataxia telangiectasia group D-associated protein

  • tripartite motif containing protein 29
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunoprecipitation
      View All» Entrez Gene Summary: The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]. View All» UniProt Summary: FUNCTION: It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.SUBUNIT STRUCTURE: Interacts with VIM and HINT1. SUBCELLULAR LOCATION: Cytoplasm. Note: Colocalizes with intermediate filaments. TISSUE SPECIFICITY: Expressed in placenta, prostate and thymus. PTM: Constitutively phosphorylated by PKC on serine/threonine in A431 cells. SEQUENCE SIMILARITIES: Contains 1 B box-type zinc finger. View All» Product Name: Anti-ATDC View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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