货号：ABD75

品牌：Merck Millipore

规格：100Ug

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-THAP11 (Ronin) Antibody | ABD75 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~48 kDa observed. Uncharacterized bands appear at ~20-25 kDa in some lysates. View All» Immunogen: KLH-conjugated linear peptide corresponding to human THAP11. View All» Background Information: THAP11 (Ronin) is a transcriptional repressor which is predominantly expressed in embryonic stem (ES) cells. It contains a THAP-type zinc finger domain which is characteristic of the THAP 11 family members. In ES cells, THAP11 interacts with the transcriptional co-regulator HCF-1, to recruit chromatin-modifying proteins such as members of the polycomb family of proteins, to induce gene repression. THAP11 targets genes involved in metabolism, transcriptional initiation, and messenger RNA splicing. It plays an important role in maintaining the pluripotent state of ES cells. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with Mouse. Predicted to react with Rat based on 100% sequence homology. Predicted to react with Human based on immunogen design. View All» Application Notes: Western Blot Analysis: 1 µg/mL from a representative lot detected THAP11 on 10 µg of mouse liver tissue lysate.Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected THAP11 in mouse cardiac muscle and mouse liver tissues. View All» Control: Mouse heart tissue lysate View All» Quality Assurance: Evaluated by Western Blot in mouse heart tissue lysate.Western Blot Analysis: 1 µg/mL of this antibody detected THAP11 on 10 µg of mouse heart tissue lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q96EK4 View All» Entrez Gene Number: NP_065190 View All» Gene Symbol: THAP11 View All» Alternate Names: THAP domain-containing protein 11 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:

• Western Blotting

• Immunohistochemistry
  View All» Product Name: Anti-THAP11 (Ronin) View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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