货号：ABD11

品牌：Merck Millipore

规格：EA

目录价：￥3732.00

市场价格：￥3172.20

会员价格：￥2985.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Threonine Dehydrogenase (TDH) Antibody | ABD11 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~37 kDa observed. A non-specific band appears at ~60 kDa. View All» Epitope: Unknown View All» Immunogen: KLH-conjugated linear peptide corresponding to mouse Threonine Dehydrogenase (TDH). View All» Isotype: IgG View All» Background Information: L-threonine is a critical amino acid with a multifarious degradative pathway. Threonine can be catabolized by either threonine dehydratase, threonine dehydrogenase, or a complex of threonine dehydrogenase and aminoacetone synthase known as threonine cleavage complex. Threonine dehydrogenase oxidizes threonine in an NAD-linked reaction that constructs α-amino-β-ketobutyrate or (AKB), which is in turn cleaved by aminoacetone synthase, converting L-threonine to glycine. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with mouse. View All» Application Notes: Immunohistochemistry Analysis: A previous lot was used by an independent laboratory to detect Threonine Dehydrogenase (TDH) in mouse embryonic stem cells (Wang, J., et al., 2009). View All» Control: Mouse embryonic stem cell lysate View All» Quality Assurance: Evaluated by Western Blot in mouse embryonic stem cell lysate.Western Blot Analysis: A 1:1,000 dilution of this antibody detected Threonine Dehydrogenase (TDH) in 10 µg of mouse embryonic stem cell lysate. View All» Purification Method: Unpurified View All» Presentation: Rabbit polyclonal serum containing 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: Q8K3F7 View All» Entrez Gene Number: NP_067455 View All» Gene Symbol: TDH View All» Alternate Names: L-threonine dehydrogenase View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:

• Western Blotting

• Immunohistochemistry
  View All» UniProt Summary: CATALYTIC ACTIVITY: L-threonine + NAD+ = L-2-amino-3-oxobutanoate + NADH. UniProtKB Q8MIR0PATHWAY: Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 1/2.SUBCELLULAR LOCATION: Mitochondrion (By similarity). UniProtKB Q8MIR0. SEQUENCE SIMILARITIES: Belongs to the sugar epimerase family. View All» Product Name: Anti-Threonine Dehydrogenase (TDH) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»
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