货号:ABC292
品牌:Merck Millipore
规格:
目录价:¥4025.00
市场价格:¥3421.25
会员价格:¥3220.00
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Description:
Anti-CHMP2B
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Molecular Weight:
~32 kDa observed
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Immunogen:
Histidine-tagged recombinant protein corresponding to human CHMP2B.
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Background Information:
Charged multivesicular body protein 2b (CHMP2B) is a member of the SNF7 family. It is a component of the endosomal sorting complex required for transport III (ESCRT-III), which involves endosomal and autophagic trafficking of proteins to lysosomes for degradation. CHMP2B is expressed in brain, heart, skeletal muscle, spleen, kidney, liver, small intestine, pancreas, lung, placenta and leukocytes. Mutations of CHMP2B have been associated with frontotemporal lobar degeneration (FTLD).
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Species Reactivity:
Human
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Control:
SH-SY5Y cell lysate
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Quality Assurance:
Evaluated by Western Blotting in SH-SY5Y cell lysate.Western Blotting Analysis: A 1:800 dilution of this antibody detected CHMP2B in 30 µg of SH-SY5Y cell lysate.
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Purification Method:
Antigen Affinity purified
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Presentation:
Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide and 50% glycerol.
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Storage Conditions:
Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
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UniProt Number:
Q9UQN3
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Gene Symbol:
CHMP2B
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Alternate Names:
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Charged multivesicular body protein 2b
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CHMP2.5
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Chromatin-modifying protein 2b
-
CHMP2b
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Vacuolar protein sorting-associated protein 2-2
-
Vps2-2
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hVps2-2
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CHMP2B
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
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Product Name:
Anti-CHMP2B
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Concentration:
0.29 mg/mL
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Antibody Type:
Polyclonal Antibody
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Qty/Pk:
150 µL
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Format:
Affinity Purified
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Host:
Rabbit
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