货号：ABC23

品牌：Merck Millipore

规格：

目录价：￥4383.00

市场价格：￥3725.55

会员价格：￥3506.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-ATG9 Antibody | ABC23 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes isoform 1 of ATG9. View All» Molecular Weight: ~87 kDa observed. Uncharacterized bands may appear at ~48 kDa and ~68 kDa in some lysates. View All» Epitope: Lumenal Region View All» Immunogen: KLH-conjugated linear peptide corresponding to the lumenal region of human ATG9. View All» Background Information: ATG9 (autophagy-related 9) is an integral membrane protein that is necessary for autophagy and the cytoplasm-to-vacuole pathway. It moves from the Golgi to the endosomes, which indicates the Golgi's role in the autophagic pathway. ATG9 has been implicated as a membrane carrier. ATG9 is required for the formation of the phagophore assembly site. View All» Species Reactivity:

• Human

• Mouse

• Rat

• Rhesus Macaque

• Chimpanzee

• Canine
  View All» Species Reactivity Note: Demonstrated to react with Human. Predicted to react with Mouse, Rat, Rhesus Macaque, Chimpanzee, and Canine based on 100% sequence homology. View All» Application Notes: Immunohistochemistry Analysis: A 1:600 dilution from a representative lot detected ATG9 in metastatic breast carcinoma in the brain, Hodgkin's Lymphoma, B-cell lymphoma, renal carcinoma, and kidney clear cell carcinoma tissues. View All» Control: Jurkat cell lysate View All» Quality Assurance: Evaluated by Western Blot in Jurkat cell lysate.Western Blot Analysis: 0.1 µg/mL of this antibody detected ATG9 in 10 µg of Jurkat cell lysate. View All» Purification Method: Affinity Purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q7Z3C6 View All» Entrez Gene Number: NP_001070666 View All» Gene Symbol:
  • ATG9A

  • APG9L1
    View All» Alternate Names:
    • Autophagy-related protein 9A

    • APG9-like 1

    • mATG9
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry (Paraffin)
        View All» UniProt Summary: FUNCTION: Plays a role in autophagy. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and FAM48A. SUBUNIT STRUCTURE: Interacts with FAM48A. SUBCELLULAR LOCATION: Cytoplasmic vesicle › autophagosome membrane; Multi-pass membrane protein (By similarity). Golgi apparatus › trans-Golgi network membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein Ref.8. SEQUENCE SIMILARITIES: Belongs to the ATG9 family.SEQUENCE CAUTION: The sequence BAB13882.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence BAB15246.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence BAB55119.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. View All» Product Name: Anti-ATG9 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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