货号：ABC105

品牌：Merck Millipore

规格：

目录价：￥4502.00

市场价格：￥3826.70

会员价格：￥3601.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Phospho-Src (Tyr419) Antibody | ABC105 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes Src phosphorylated at Tyr419. View All» Molecular Weight: ~60 kDa observed View All» Epitope: Phosphorylated Tyr419 View All» Immunogen: KLH-conjugated linear peptide corresponding to human Src phosphorylated at Tyr419. View All» Background Information: Src is a ubiquitous non-receptor tyrosine kinase with relatively high levels of expression in neurons, osteoclasts, and platelets. It couples many different classes of cell surface receptors, including immune receptors, integrins, receptor tyrosine kinases, and cytokine receptors, to their respective intracellular signaling networks. Src recognizes activated cell surface receptors as dimers or clusters, and phosphorylates their tyrosine residues, providing binding motifs for signaling molecules. By this mechanism, Src facilitates a number of signaling pathways involved in cell adhesion, cell cycle, apoptosis, gene transcription, and cell migration. Src may also play a role in tumor development. Src is regulated by phosphorylation at multiple tyrosine residues. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. Predicted to react with Mouse and Rat based on 100% sequence homology. View All» Control: COS1 transfected with wildtype Src View All» Quality Assurance: Evaluated by Western Blot/Peptide Inhibition Assay in COS1 transfected with wildtype Src.Western Blot Analysis: 0.02 µg/mL of this antibody detected Src on 10 µg of COS1 transfected with wildtype Src. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P12931 View All» Entrez Gene Number: NP_005408 View All» Gene Symbol:

• SRC

• SRC1
  View All» Alternate Names:
  • Proto-oncogene tyrosine-protein kinase Src

  • Proto-oncogene c-Src

  • pp60c-src

  • p60-Src
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Peptide Inhibition Assay
      View All» Product Name: Anti-Phospho-Src (Tyr419) View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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