货号：AB9698

品牌：Merck Millipore

规格：500UL

目录价：￥5974.00

市场价格：￥5077.90

会员价格：￥4779.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Neuron Specific Enolase (NSE) Antibody | AB9698 View All» Replaces: AB5619 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Neuron Specific Enolase (NSE). View All» Immunogen: Synthetic peptides from human/rat/mouse Neuron Specific Enolase. View All» Species Reactivity:

• Human

• Rat

• Mouse
  View All» Application Notes: Immunohistochemistry: 1:50-1:100 using 2% paraformaldehyde fixed tissues. Immunocytochemistry: 1:50-1:100 using 2% paraformaldehyde fixed cells. Western blotting: On mouse brain extracts, blot shows a single band at 47 kDa. Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified chicken IgY. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. View All» UniProt Number: P09104 View All» Entrez Gene Number: NM_001975.2 View All» Gene Symbol:
  • ENO2

  • NSE

  • Gamma-enolase

  • EC 4.2.1.11
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. View All» UniProt Summary: FUNCTION: SwissProt: P09104 # Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).COFACTOR: Magnesium. Required for catalysis and for stabilizing the dimer.SIZE: 434 amino acids; 47269 Da SUBUNIT: Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific.SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell membrane (By similarity). Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form (By similarity).TISSUE SPECIFICITY: The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.DEVELOPMENTAL STAGE: During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells.SIMILARITY: SwissProt: P09104 ## Belongs to the enolase family. View All» Brand Family: Chemicon View All» Product Name: Anti-Neuron Specific Enolase (NSE) Antibody | AB9698 View All» Concentration: 0.2 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 500 µL View All» Target / Localization: Cytoplasmic View All» Format: Affinity Purified View All» Host: Chicken View All»
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